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Study · Randomized controlled trial · n = 30 · 2000

3 results

Effectiveness of low dose of gonadotropin releasing hormone agonist on hormonal flare-up.

Bständig B, Cédrin-Durnerin I, Hugues JN

Journal of assisted reproduction and genetics1 Feb 2000Cited by 5 (Europe PMC)

PMID10806591 (opens in a new tab)PMCIDPMC3455162 (opens in a new tab)DOI10.1023/a:1009470101732 (opens in a new tab)PepBankPUB-10806591
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In normo-ovulatory women, FSH release did not differ significantly between low and standard triptorelin doses.

    In plain wordsIn women, FSH release did not differ significantly between low and standard triptorelin doses.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeFSH release
    Study

    n = 30

    Comparator
    100 micrograms triptorelin
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    25 micrograms versus 100 micrograms · three daysAs given in this study (human).

    Source sentences

    Summary
    No significant difference in the magnitude of FSH and E2 release could be observed following administration of the two doses of agonist whereas maximal plasma LH level was significantly reduced after injection of 25 micrograms of triptorelin.
    2 context sentences
    Summary · context
    The gonadotroph (FSH, LH) and steroid [estradiol (E2) and progesterone (P)] flare-up was studied on two consecutive cycles in 30 normo-ovulatory women.
    Summary · context
    Patients were randomized to receive either 25 or 100 micrograms of triptorelin for three days at the beginning of the first cycle. Then doses were switched according to a crossing over design in the second cycle.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In normo-ovulatory women, estradiol release did not differ significantly between low and standard triptorelin doses.

    In plain wordsIn women, estradiol release did not differ significantly between low and standard triptorelin doses.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeEstradiol release
    Study

    n = 30

    Comparator
    100 micrograms triptorelin
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    25 micrograms versus 100 micrograms · three daysAs given in this study (human).

    Source sentences

    Summary
    No significant difference in the magnitude of FSH and E2 release could be observed following administration of the two doses of agonist whereas maximal plasma LH level was significantly reduced after injection of 25 micrograms of triptorelin.
    2 context sentences
    Summary · context
    The gonadotroph (FSH, LH) and steroid [estradiol (E2) and progesterone (P)] flare-up was studied on two consecutive cycles in 30 normo-ovulatory women.
    Summary · context
    Patients were randomized to receive either 25 or 100 micrograms of triptorelin for three days at the beginning of the first cycle. Then doses were switched according to a crossing over design in the second cycle.
  3. 03HumanRandomized controlled trialEfficacy outcome

    In normo-ovulatory women, low-dose triptorelin reduced maximal plasma LH compared with the standard dose.

    In plain wordsIn women, low-dose triptorelin reduced peak LH compared with the standard dose.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    DecreaseMaximal plasma LH
    Study

    n = 30

    Comparator
    100 micrograms triptorelin
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    25 micrograms versus 100 micrograms · three daysAs given in this study (human).

    Source sentences

    Summary
    No significant difference in the magnitude of FSH and E2 release could be observed following administration of the two doses of agonist whereas maximal plasma LH level was significantly reduced after injection of 25 micrograms of triptorelin.
    2 context sentences
    Summary · context
    The gonadotroph (FSH, LH) and steroid [estradiol (E2) and progesterone (P)] flare-up was studied on two consecutive cycles in 30 normo-ovulatory women.
    Summary · context
    Patients were randomized to receive either 25 or 100 micrograms of triptorelin for three days at the beginning of the first cycle. Then doses were switched according to a crossing over design in the second cycle.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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