Skip to content

Study · Measured the body's own peptide · 2000

3 results

Characterization of a 5'-flanking region supporting the transcription of mouse thymosin beta-4 in mouse NIH3T3 cells.

Su Y, Chang SL, Hsiao HL

Molecular and cellular biochemistry1 Jan 2000Cited by 5 (Europe PMC)

PMID10724345 (opens in a new tab)DOI10.1023/a:1007020619788 (opens in a new tab)PepBankPUB-10724345
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured1

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelIn vitro (cells)Mechanism

    In mouse NIH3T3 cells, interferon-alpha rapidly activated the cells' own Tbeta-4 gene.

    In plain wordsIn mouse cells, interferon-alpha quickly raised the activity of the cells' own thymosin beta‑4 gene.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseEndogenous Tbeta-4 gene activation by interferon-alpha
    Study

    mousen: not reported in source

    NIH3T3 cells
    Outcome group
    Gene expression · Whole body

    Source sentences

    Summary
    a rapid activation of endogenous Tbeta-4 gene by this cytokine was observed.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

Studies that did not test the peptide alone2

In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin beta-4 (human).

  1. 02LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cells)Mechanism

    In mouse NIH3T3 cells, the DNA fragment from -278 to +410 of the mouse Tbeta-4 gene directed expression of a reporter gene.

    In plain wordsIn mouse cells, a stretch of the thymosin beta‑4 gene could switch on a test gene.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicablePromoter activity of the Tbeta-4 gene fragment (-278 to +410)
    Study

    mousen: not reported in source

    NIH3T3 cells
    Outcome group
    Gene expression · Whole body

    Source sentences

    Summary
    demonstrated that the DNA fragment from -278 to +410 of this gene was capable of directing the expression of a chloramphenicol acetyltransferase reporter gene in NIH3T3 cells.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

  2. 03LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cells)Mechanism

    In mouse NIH3T3 cells, interferon-alpha treatment did not induce reporter gene expression driven by the Tbeta-4 gene fragment.

    In plain wordsIn mouse cells, interferon-alpha did not switch on the test gene linked to part of the thymosin beta‑4 gene.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    No significant changeInterferon-alpha induction of reporter gene expression
    Study

    mousen: not reported in source

    NIH3T3 cells
    Outcome group
    Gene expression · Whole body

    Source sentences

    Summary
    expression of the reporter gene in cells cannot be induced by interferon-alpha treatment

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.