In boys with constitutional delay of puberty, serum inhibin B was inversely related to GnRH-stimulated FSH concentrations and to the rise from basal to peak FSH.
In plain wordsIn boys with delayed puberty, higher inhibin B was linked to a smaller FSH rise in a GnRH test.
- Peptide
- Gonadorelin (GnRH, LHRH)
- Outcome
- Not applicableInhibin B versus GnRH-stimulated FSH
- Study
n = 25
- Outcome group
- Sex hormones and fertility · Endocrine and hormones
Measurements
- Correlation with stimulated FSH
- −0.45 to −0.43 r(S)
- inhibin B
- Correlation with FSH rise
- −0.63 r(S)
- inhibin B
Source sentences
However, inhibin B and GnRH-stimulated FSH concentrations (r(S)= -0.43 to -0.45, n=25, P<0.05) and the difference between basal and peak serum FSH levels were inversely related (r(S)= -0.63, n=25, P<0.005).
2 context sentences(design, population, supporting numbers)
Twenty-five boys with constitutional delay of puberty (CDP; 20 in Tanner stage G2 and 5 in G3; age range, 13.
5-16.8 years) and eight prepubertal boys (G1P1) with GD (age range, 10.0-13.2 years) were clinically examined, and serum inhibin B, testosterone and estradiol concentrations were measured from sera obtained immediately before the administration of GnRH (Relefact; 3.5 microgram/kg, maximum 100 microgram i.v.).
In this study, Gonadorelin (GnRH, LHRH) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Gonadorelin (GnRH, LHRH).