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Study · Animal study (in vivo) · dog · 1999

3 results

Six-week treatment with hexarelin in young dogs: evaluation of the GH responsiveness to acute hexarelin or GHRH administration, and of the orexigenic effect of hexarelin.

Rigamonti AE, Cella SG, Marazzi N, Müller EE

European journal of endocrinology1 Sept 1999Cited by 7 (Europe PMC)

PMID10474131 (opens in a new tab)DOI10.1530/eje.0.1410313 (opens in a new tab)PepBankPUB-10474131
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Activity measurement

    In young beagle dogs, the GH peak response to acute hexarelin first increased, peaking at week 3, then fell below basal values at week 6 of hexarelin treatment.

    In plain wordsIn dogs, the growth hormone response to hexarelin first rose during 6 weeks of hexarelin, then fell below the starting level.

    Peptide
    Hexarelin
    Outcome
    MixedGH response to acute hexarelin after chronic hexarelin
    Study

    dogn = 6

    Young beagle dogs
    Comparator
    Before treatment
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    250 microg/kg twice daily · subcutaneous · 6 weeksAs given in this study (dog).

    Source sentences

    Summary
    The GH peak response to acute hexarelin or GHRH initially increased, with a maximum observed at the 3rd week, and then decreased to basal values (GHRH) or less (hexarelin) at the 6th week.
    1 context sentence
    Summary · context
    In this study we evaluated, in six young (5-7 year-old) beagle dogs, the effects of a 6-week administration of hexarelin
  2. 02AnimalAnimal study (in vivo)Activity measurement

    In young beagle dogs, the GH peak response to acute GHRH first increased, peaking at week 3, then returned to basal values at week 6 of hexarelin treatment.

    In plain wordsIn dogs, the growth hormone response to GHRH first rose during 6 weeks of hexarelin, then returned to the starting level.

    Peptide
    Hexarelin
    Outcome
    MixedGH response to acute GHRH after chronic hexarelin
    Study

    dogn = 6

    Young beagle dogs
    Comparator
    Before treatment
    Outcome group
    Growth hormone and IGF-1 · Endocrine and hormones
    Studied dose
    250 microg/kg twice daily · subcutaneous · 6 weeksAs given in this study (dog).

    Source sentences

    Summary
    The GH peak response to acute hexarelin or GHRH initially increased, with a maximum observed at the 3rd week, and then decreased to basal values (GHRH) or less (hexarelin) at the 6th week.
    1 context sentence
    Summary · context
    In this study we evaluated, in six young (5-7 year-old) beagle dogs, the effects of a 6-week administration of hexarelin
  3. 03AnimalAnimal study (in vivo)Efficacy outcome

    In young beagle dogs, the acute feeding response to hexarelin was abolished at week 3 of treatment and returned to normal at week 6.

    In plain wordsIn dogs, the eating response to hexarelin disappeared at week 3 of treatment and was back to normal at week 6.

    Peptide
    Hexarelin
    Outcome
    MixedAcute feeding response to hexarelin
    Study

    dogn = 6

    Young beagle dogs
    Comparator
    Before treatment
    Outcome group
    Appetite and food intake · Metabolic and weight
    Studied dose
    250 microg/kg twice daily · subcutaneous · 6 weeksAs given in this study (dog).

    Source sentences

    Summary
    Parallel evaluation of the acute orexigenic effect of hexarelin evinced a different time-course of the behavioural response, namely an acute feeding response to hexarelin that was abolished at the 3rd week and returned to normal at the 6th week.
    1 context sentence
    Summary · context
    In this study we evaluated, in six young (5-7 year-old) beagle dogs, the effects of a 6-week administration of hexarelin

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

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