Effects of anabolic-androgenic steroid use or gonadal testosterone suppression on serum leptin concentration in men.

Hislop MS, Ratanjee BD, Soule SG, Marais AD

European journal of endocrinology1 Jul 1999Cited by 36 (Europe PMC)

PMID10407221DOI10.1530/eje.0.1410040PepBankPUB-10407221

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

01HumanNon-randomized trialEfficacy outcome
In healthy men, triptorelin significantly reduced testosterone after 5 weeks.
In plain wordsIn healthy men, triptorelin lowered testosterone after 5 weeks.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseSerum testosterone
Study
n = 9
Comparator
Baseline
Outcome group
Sex hormones and fertility · Endocrine and hormones
Studied dose
Dose not stated · intramuscular · 5 weeksAs given in this study (human).
Measurements
Testosterone
7.32 ng/ml
baseline
Testosterone
1.15 ng/ml
5 weeks
Source sentences
Summary
Testosterone concentration was significantly reduced by triptorelin administration (7.32+/- 1.92ng/ml at baseline compared with 1.15+/-0.57ng/ml at 5 weeks, P=0.002).
1 context sentence(design, population, supporting numbers)
Summary · context
The effects of sex steroid suppression on serum leptin concentration were investigated in nine healthy men in whom testosterone had been reversibly suppressed for 5 weeks after treatment with intramuscular triptorelin.
Report a problemFND-1040722101
02HumanNon-randomized trialEfficacy outcome
In healthy men, triptorelin did not significantly change body fat percentage.
In plain wordsIn healthy men, triptorelin did not significantly change body fat percentage.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeBody fat percentage
Study
n = 9
Comparator
Baseline
Outcome group
Body weight · Metabolic and weight
Studied dose
Dose not stated · intramuscular · 5 weeksAs given in this study (human).
Source sentences
Summary
Body fat percentage was unaffected by the AAS or triptorelin intervention (P>0.19).
1 context sentence(design, population, supporting numbers)
Summary · context
The effects of sex steroid suppression on serum leptin concentration were investigated in nine healthy men in whom testosterone had been reversibly suppressed for 5 weeks after treatment with intramuscular triptorelin.
Report a problemFND-1040722102
03HumanNon-randomized trialEfficacy outcome
In healthy men, triptorelin significantly increased leptin after five weeks.
In plain wordsIn healthy men, triptorelin raised leptin after five weeks.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
IncreaseSerum leptin
Study
n = 9
Comparator
Baseline
Outcome group
Appetite and food intake · Endocrine and hormones
Studied dose
Dose not stated · intramuscular · 5 weeksAs given in this study (human).
Measurements
Leptin
6.63 ng/ml
five weeks
Source sentences
Summary
was significantly increased by triptorelin administration (2. 96+/-1.50ng/ml at baseline compared with 6.63+/-4.67ng/ml at five weeks, P=0.004).
1 context sentence(design, population, supporting numbers)
Summary · context
The effects of sex steroid suppression on serum leptin concentration were investigated in nine healthy men in whom testosterone had been reversibly suppressed for 5 weeks after treatment with intramuscular triptorelin.
Report a problemFND-1040722103

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
22 Oct 2026, 02:26 UTC
Study results updated
Version 1
21 Oct 2026, 18:59 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

MeSH terms

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