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Study · Randomized controlled trial · n = 14 · 1998

2 results

Prehospital treatment of severe hypoglycaemia: a comparison of intramuscular glucagon and intravenous glucose.

Carstens S, Sprehn M

Prehospital and disaster medicine1 Apr 1998Cited by 19 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In patients with severe hypoglycaemia, recovery took significantly longer with glucagon than intravenous glucose: 8 to 21 versus 1 to 3 minutes.

    In plain wordsIn patients with severe hypoglycaemia, recovery took longer with glucagon than intravenous glucose.

    Peptide
    Glucagon
    Outcome
    IncreaseTime to recovery
    Study

    n = 14

    Comparator
    Intravenous glucose
    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    1 mg · intramuscularAs given in this study (human).

    Measurements

    Recovery time
    8 to 21 minutes
    glucagon
    Recovery time
    1 to 3 minutes
    intravenous glucose

    Source sentences

    Summary
    Recovery time ranged for 1 to 3 minutes for those receiving glucose intravenously and 8 to 21 minutes for those receiving intramuscular glucagon.
    2 context sentences
    Summary · context
    Recovery time between the two groups was significantly different statistically.
    Summary · context
    14 patients with IDDM with severe hypoglycaemia requiring treatment by the medical staff was randomised to treatment either with 50 ml of 50% glucose intravenously or intramuscular 1 mg glucagon.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In patients with severe hypoglycaemia, glucose increased steadily after glucagon, whereas intravenous glucose produced greater fluctuations.

    In plain wordsIn patients with severe hypoglycaemia, glucose increased steadily after glucagon and fluctuated more after intravenous glucose.

    Peptide
    Glucagon
    Outcome
    MixedGlycaemia profile
    Study

    n = 14

    Comparator
    Intravenous glucose
    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    1 mg · intramuscularAs given in this study (human).

    Source sentences

    Summary
    Characteristic glycaemia profiles were identified and differences were present between the two groups with a greater fluctuating pattern for the glucose group compared to the steadily increasing pattern seen after glucagon treatment.
    1 context sentence
    Summary · context
    14 patients with IDDM with severe hypoglycaemia requiring treatment by the medical staff was randomised to treatment either with 50 ml of 50% glucose intravenously or intramuscular 1 mg glucagon.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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