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Study · Not a test of the peptide alone · 1999

1 result

The same molecular defects of the gonadotropin-releasing hormone receptor determine a variable degree of hypogonadism in affected kindred.

de Roux N, Young J, Brailly-Tabard S, Misrahi M, Milgrom E, Schaison G

The Journal of clinical endocrinology and metabolism1 Feb 1999Cited by 79 (Europe PMC)

PMID10022417 (opens in a new tab)DOI10.1210/jcem.84.2.5449 (opens in a new tab)PepBankPUB-10022417
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  1. 01HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneCase report or seriesActivity measurement

    In a man with complete idiopathic hypogonadotropic hypogonadism and GnRH receptor mutations, triptorelin elicited no response.

    In plain wordsIn a man with severe reproductive hormone deficiency and GnRH receptor mutations, triptorelin produced no response.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeGonadotropin response
    Study

    n = 1

    Outcome group
    Sex hormones and fertility · Endocrine and hormones

    Source sentences

    Summary
    The propositus, a 30-yr-old man, displayed complete idiopathic hypogonadotropic hypogonadism with extremely low plasma levels of gonadotropins, absence of pulsatility of endogenous LH and alpha-subunit, absence of response to GnRH and GnRH agonist (triptorelin), and absence of effect of pulsatile ad…
    1 context sentence
    Summary · context
    Detailed endocrinological studies were performed in the three affected kindred of a family carrying mutations of the GnRH receptor gene.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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