In wild male Hawaiian monk seals, triptorelin significantly reduced circulating testosterone from 1.01 to 0.21 ng/ml approximately 38 days later.
In plain wordsIn wild male Hawaiian monk seals, circulating testosterone decreased significantly after triptorelin compared with initial levels.
- Outcome
- DecreaseCirculating testosterone
- Study
Monachus schauinslandin = 8
Wild adult male Hawaiian monk seals- Outcome group
- Sex hormones and fertility · Endocrine and hormones
- Studied dose
- 7.5 mgAs given in this study (Monachus schauinslandi).
Measurements
- Testosterone
- 1.01 ng/ml
- first sample
- Testosterone
- 0.21 ng/ml
- second sample approximately 38 days later
Source sentences
In the treated group, the agonist induced a significant decline in mean circulating testosterone concentrations, from 1.01 ng/ml (first sample) to 0.21 ng/ml (second sample, taken approximately 38 days later).
3 context sentences(design, population, supporting numbers)
A gonadotropin-releasing hormone (GnRH) agonist, d-Trp6-LHRH, was evaluated for its effectiveness in reducing circulating testosterone concentrations in wild Hawaiian monk seals (Monachus schauinslandi).
Twenty-eight adult male seals were randomly divided into three groups: 10 were captured and treated with 7.5 mg of the GnRH agonist, 9 were captured but did not receive the agonist, and 9 were captured near the end of the study to serve as handling controls.
From 14 to 58 days after initial capture, 8 of the treated seals and 8 of the untreated seals were recaptured and a second sample of blood was taken.