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Study · Non-randomized trial · n = 37 · 1998

2 results

The increased circulating prostate-specific antigen concentrations in women with hirsutism do not respond to acute changes in adrenal or ovarian function.

Escobar-Morreale HF, Serrano-Gotarredona J, Avila S, Villar-Palasí J, Varela C, Sancho J

The Journal of clinical endocrinology and metabolism1 Jul 1998Cited by 23 (Europe PMC)

PMID9661648 (opens in a new tab)DOI10.1210/jcem.83.7.4960 (opens in a new tab)PepBankPUB-09661648
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In hirsute women, PSA did not change from baseline during ovarian stimulation after triptorelin.

    In plain wordsIn women with excess hair growth, PSA did not change during ovarian stimulation after triptorelin.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changePSA after gonadal stimulation
    Study

    n = 37

    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    3.75 mg single dose · intramuscular · 1 dayAs given in this study (human).

    Source sentences

    Summary
    PSA levels did not change during ovarian or adrenal stimulation or during gonadal suppression with respect to initial values.
    2 context sentences
    Summary · context
    Thirty-seven hirsute women were studied in the follicular phase of the menstrual cycle.
    Summary · context
    Basal and ACTH-stimulated plasma samples were obtained, and sampling was repeated 1 (gonadal stimulation) and 21 (gonadal suppression) days after receiving a single im 3.75-mg dose of triptorelin.
  2. 02HumanNon-randomized trialEfficacy outcome

    In hirsute women, PSA did not change from baseline during gonadal suppression after triptorelin.

    In plain wordsIn women with excess hair growth, PSA did not change during gonadal suppression after triptorelin.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changePSA after gonadal suppression
    Study

    n = 37

    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    3.75 mg single dose · intramuscular · 21 daysAs given in this study (human).

    Source sentences

    Summary
    PSA levels did not change during ovarian or adrenal stimulation or during gonadal suppression with respect to initial values.
    2 context sentences
    Summary · context
    Thirty-seven hirsute women were studied in the follicular phase of the menstrual cycle.
    Summary · context
    Basal and ACTH-stimulated plasma samples were obtained, and sampling was repeated 1 (gonadal stimulation) and 21 (gonadal suppression) days after receiving a single im 3.75-mg dose of triptorelin.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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