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Study · Measured the body's own peptide · 1998

2 results

Induction of necrosis by zinc in prostate carcinoma cells and identification of proteins increased in association with this induction.

Iguchi K, Hamatake M, Ishida R, Usami Y, Adachi T, Yamamoto H, Koshida K, Uchibayashi T, Hirano K

European journal of biochemistry1 May 1998Cited by 50 (Europe PMC)

PMID9654077 (opens in a new tab)DOI10.1046/j.1432-1327.1998.2530766.x (opens in a new tab)PepBankPUB-09654077
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelIn vitro (cells)Mechanism

    In PC-3 prostate carcinoma cells, zinc-induced necrosis was associated with an increase in thymosin beta4.

    In plain wordsIn cells, the body's own thymosin beta4 rose when zinc caused prostate cancer cells to die.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseThymosin beta4 increase with zinc-induced necrosis
    Study

    humann: not reported in source

    PC-3 prostate carcinoma cells
    Outcome group
    Tumor growth · Cancer

    Source sentences

    Summary
    Associated with the induction of necrosis was an increase in low molecular-mass proteins
    1 context sentence
    Summary · context
    and thymosin beta4, parathymosin and metallothionein in PC-3.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelIn vitro (cells)Mechanism

    In PC-3 cells, the time course of the increase of thymosin beta4 was consistent with the appearance of cell detachment and dead cells.

    In plain wordsIn cells, the rise in the body's own thymosin beta4 followed the same timing as cells detaching and dying.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseThymosin beta4 time course versus cell detachment
    Study

    humann: not reported in source

    PC-3 prostate carcinoma cells
    Outcome group
    Tumor growth · Cancer

    Source sentences

    Summary
    The time course of the increase of thymosin beta10 in LNCaP cells and thymosin beta4 in PC-3 cells
    1 context sentence
    Summary · context
    was consistent with that of appearance of cell detachment and dead cells.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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