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Study · Not a test of the peptide alone · 1997

7 results

Natural and synthetic thymic peptides as therapeutics for immune dysfunction.

Morozov VG, Khavinson VK

International journal of immunopharmacology1 Sept 1997Cited by 37 (Europe PMC)

PMID9637345 (opens in a new tab)DOI10.1016/s0192-0561(97)00058-1 (opens in a new tab)PepBankPUB-09637345
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study7

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone7

In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymalin.

  1. 01LabNot a test of Thymalin aloneIn vitro (cells)Mechanism

    In cells, pooled natural and synthetic thymic pharmaceuticals, including Thymalin, activated T-cell differentiation.

    In plain wordsIn cells, natural and synthetic thymic pharmaceuticals, including Thymalin, activated T-cell differentiation.

    Peptide
    Thymalin
    Outcome
    IncreaseT-cell differentiation
    Study

    n: not reported in source

    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Both natural and synthetic pharmaceuticals activated T-cell differentiation
    1 context sentence
    Summary · context
    Pharmaceutical containing natural peptides (Thymalin) was put into practice as immunocorrector.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  2. 02LabNot a test of Thymalin aloneIn vitro (cells)Mechanism

    In cells, pooled natural and synthetic thymic pharmaceuticals, including Thymalin, activated T-cell recognition of peptide-MHC complexes.

    In plain wordsIn cells, natural and synthetic thymic pharmaceuticals, including Thymalin, activated T-cell recognition of peptide-MHC complexes.

    Peptide
    Thymalin
    Outcome
    IncreaseT-cell recognition of peptide-MHC complexes
    Study

    n: not reported in source

    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Both natural and synthetic pharmaceuticals activated T-cell differentiation, T-cell recognition of peptide-MHC complexes
    1 context sentence
    Summary · context
    Pharmaceutical containing natural peptides (Thymalin) was put into practice as immunocorrector.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  3. 03LabNot a test of Thymalin aloneIn vitro (cells)Mechanism

    In cells, pooled natural and synthetic thymic pharmaceuticals, including Thymalin, changed intracellular cyclic nucleotide composition.

    In plain wordsIn cells, natural and synthetic thymic pharmaceuticals, including Thymalin, changed intracellular cyclic nucleotide composition.

    Peptide
    Thymalin
    Outcome
    Direction not reportedIntracellular cyclic nucleotide composition
    Study

    n: not reported in source

    Outcome group
    Receptor activity and mechanism · Immune and inflammation

    Source sentences

    Summary
    Both natural and synthetic pharmaceuticals activated T-cell differentiation, T-cell recognition of peptide-MHC complexes, induced the changes in intracellular composition of cyclic nucleotides and cytokine [interleukin (IL-2), interferon (IFN)] excretion of blood lymphocytes.
    1 context sentence
    Summary · context
    Pharmaceutical containing natural peptides (Thymalin) was put into practice as immunocorrector.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  4. 04LabNot a test of Thymalin aloneIn vitro (cells)Mechanism

    In blood lymphocytes, pooled natural and synthetic thymic pharmaceuticals, including Thymalin, changed IL-2 excretion.

    In plain wordsIn cells, natural and synthetic thymic pharmaceuticals, including Thymalin, changed IL-2 release.

    Peptide
    Thymalin
    Outcome
    Direction not reportedIL-2 excretion
    Study

    n: not reported in source

    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Both natural and synthetic pharmaceuticals activated T-cell differentiation, T-cell recognition of peptide-MHC complexes, induced the changes in intracellular composition of cyclic nucleotides and cytokine [interleukin (IL-2), interferon (IFN)] excretion of blood lymphocytes.
    1 context sentence
    Summary · context
    Pharmaceutical containing natural peptides (Thymalin) was put into practice as immunocorrector.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  5. 05LabNot a test of Thymalin aloneIn vitro (cells)Mechanism

    In blood lymphocytes, pooled natural and synthetic thymic pharmaceuticals, including Thymalin, changed interferon excretion.

    In plain wordsIn cells, natural and synthetic thymic pharmaceuticals, including Thymalin, changed interferon release.

    Peptide
    Thymalin
    Outcome
    Direction not reportedInterferon excretion
    Study

    n: not reported in source

    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Both natural and synthetic pharmaceuticals activated T-cell differentiation, T-cell recognition of peptide-MHC complexes, induced the changes in intracellular composition of cyclic nucleotides and cytokine [interleukin (IL-2), interferon (IFN)] excretion of blood lymphocytes.
    1 context sentence
    Summary · context
    Pharmaceutical containing natural peptides (Thymalin) was put into practice as immunocorrector.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  6. 06LabNot a test of Thymalin aloneIn vitro (cells)Mechanism

    In thymocytes, natural thymic peptides including Thymalin differed from synthetic dipeptides, which did not influence antioxidant response.

    In plain wordsIn cells, natural thymic peptides including Thymalin differed from synthetic dipeptides, which did not affect antioxidant response.

    Peptide
    Thymalin
    Outcome
    Direction not reportedAntioxidant response in thymocytes
    Study

    n: not reported in source

    Comparator
    Synthetic dipeptides
    Outcome group
    Receptor activity and mechanism · Immune and inflammation

    Source sentences

    Summary
    They had no influence on antioxidant response in thymocytes in comparison with natural peptides.
    2 context sentences
    Summary · context
    Synthetic dipeptides activated neutrophil chemotaxis and phagocytosis.
    Summary · context
    Pharmaceutical containing natural peptides (Thymalin) was put into practice as immunocorrector.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  7. 07LabNot a test of Thymalin aloneIn vitro (cell-free)Other

    In lab tests, reversed-phase chromatography isolated L-Glu-L-Trp from Thymalin.

    In plain wordsIn lab tests, chromatography isolated L-Glu-L-Trp from Thymalin.

    Peptide
    Thymalin
    Outcome
    Not applicableIsolation of L-Glu-L-Trp
    Study

    n: not reported in source

    Outcome group
    Peptide structure and chemistry · Pharmacology

    Source sentences

    Summary
    One of the immunomodulatory molecules (L-Glu-L-Trp) has been isolated from Thymalin by reversed-phase high performance liquid chromatography.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Versions 3 to 4Current

    21 Oct 2026, 16:35 UTC

    The same notice was added 2 times, first on 21 Oct 2026, 12:50 UTC. The status did not change between them.

    Study data updated · source update from Europe PMC

  2. Version 2

    14 Oct 2026, 05:02 UTC

    Study results updated

  3. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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