Effects of treating young boars with a GnRH depot formulation on endocrine functions, testis size, boar taint, carcass composition and muscular structure.

Schneider F, Falkenberg H, Kuhn G, Nürnberg K, Rehfeldt C, Kanitz W

Animal reproduction science1 Feb 1998Cited by 10 (Europe PMC)

PMID9615181DOI10.1016/s0378-4320(97)00086-9PepBankPUB-09615181

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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study10

10 results from studies that gave the peptide. No result from this study comes from people.

01AnimalAnimal study (in vivo)Efficacy outcome
In boars, triptorelin slightly reduced sensory boar taint at slaughter versus controls.
In plain wordsIn boars, sensory boar taint was slightly lower with triptorelin than in controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseSensory boar taint
Study
pign = 38
Young boars
Comparator
Saline
Outcome group
Non-clinical applications · Reproductive and sexual health
Studied dose
Dose not stated
Measurements
Sensory boar taint
0.76 score
treated
Sensory boar taint
0.99 score
control
Source sentences
Summary
The result of sensorial testing for boar taint detection at slaughter showed a slight reduction in this trait (0.76 vs. 0.99).
3 context sentences(design, population, supporting numbers)
Summary · context
A study was designed to determine the effects of triptorelin (Decapeptyl C.R.), a GnRH-agonist in a depot formulation, on androst-16-en-3-one (androstenone), LH, oestradiol and testosterone and on carcass composition and muscle structure in boars.
Summary · context
Treatment with this highly potent GnRH analog ensured peptide release for 4 weeks when given to 18 animals at 135 days of age (group 1).
Summary · context
Control animals (n = 20, group 2) received a saline injection.
Report a problemFND-0961518104
02AnimalAnimal study (in vivo)Efficacy outcome
In boars, fat androstenone remained below the boar-taint threshold in every triptorelin-treated animal, unlike most controls.
In plain wordsIn boars, fat androstenone remained below the boar-taint threshold with triptorelin, unlike most controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseFat androstenone
Study
pign = 38
Young boars
Comparator
Saline
Outcome group
Non-clinical applications · Reproductive and sexual health
Studied dose
Dose not stated
Measurements
Fat androstenone
< 0.5 microgram/g
all treated animals
Source sentences
Summary
The concentration of androstenone in the body fat of all treated animals was lower than the generally accepted limit of 0.5 microgram/g for the absence of boar taint, compared with the concentrations from 20 control animals among which 13 showed levels higher than this limit.
3 context sentences(design, population, supporting numbers)
Summary · context
A study was designed to determine the effects of triptorelin (Decapeptyl C.R.), a GnRH-agonist in a depot formulation, on androst-16-en-3-one (androstenone), LH, oestradiol and testosterone and on carcass composition and muscle structure in boars.
Summary · context
Treatment with this highly potent GnRH analog ensured peptide release for 4 weeks when given to 18 animals at 135 days of age (group 1).
Summary · context
Control animals (n = 20, group 2) received a saline injection.
Report a problemFND-0961518105
03AnimalAnimal study (in vivo)Efficacy outcome
In boars, triptorelin significantly reduced testis weight versus controls.
In plain wordsIn boars, triptorelin reduced testis weight compared with controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseTestis weight
Study
pign = 38
Young boars
Comparator
Saline
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
Dose not stated
Source sentences
Summary
The hormonal treatment significantly reduced the weight and size of the tests.
3 context sentences(design, population, supporting numbers)
Summary · context
A study was designed to determine the effects of triptorelin (Decapeptyl C.R.), a GnRH-agonist in a depot formulation, on androst-16-en-3-one (androstenone), LH, oestradiol and testosterone and on carcass composition and muscle structure in boars.
Summary · context
Treatment with this highly potent GnRH analog ensured peptide release for 4 weeks when given to 18 animals at 135 days of age (group 1).
Summary · context
Control animals (n = 20, group 2) received a saline injection.
Report a problemFND-0961518106
04AnimalAnimal study (in vivo)Efficacy outcome
In boars, triptorelin significantly reduced testis size versus controls.
In plain wordsIn boars, triptorelin reduced testis size compared with controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseTestis size
Study
pign = 38
Young boars
Comparator
Saline
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
Dose not stated
Source sentences
Summary
The hormonal treatment significantly reduced the weight and size of the tests.
3 context sentences(design, population, supporting numbers)
Summary · context
A study was designed to determine the effects of triptorelin (Decapeptyl C.R.), a GnRH-agonist in a depot formulation, on androst-16-en-3-one (androstenone), LH, oestradiol and testosterone and on carcass composition and muscle structure in boars.
Summary · context
Treatment with this highly potent GnRH analog ensured peptide release for 4 weeks when given to 18 animals at 135 days of age (group 1).
Summary · context
Control animals (n = 20, group 2) received a saline injection.
Report a problemFND-0961518107
05AnimalAnimal study (in vivo)Efficacy outcome
In boars, triptorelin did not affect backfat skatole versus controls.
In plain wordsIn boars, backfat skatole did not differ between triptorelin and controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeBackfat skatole
Study
pign = 38
Young boars
Comparator
Saline
Outcome group
Non-clinical applications · Reproductive and sexual health
Studied dose
Dose not stated
Measurements
Backfat skatole
0.141 microgram/g
treated
Backfat skatole
0.15 microgram/g
control
Source sentences
Summary
There was no effect on skatole levels in backfat (0.141 vs. 0.150 microgram/g).
3 context sentences(design, population, supporting numbers)
Summary · context
A study was designed to determine the effects of triptorelin (Decapeptyl C.R.), a GnRH-agonist in a depot formulation, on androst-16-en-3-one (androstenone), LH, oestradiol and testosterone and on carcass composition and muscle structure in boars.
Summary · context
Treatment with this highly potent GnRH analog ensured peptide release for 4 weeks when given to 18 animals at 135 days of age (group 1).
Summary · context
Control animals (n = 20, group 2) received a saline injection.
Report a problemFND-0961518108
06AnimalAnimal study (in vivo)Efficacy outcome
In boars, triptorelin did not influence carcass composition.
In plain wordsIn boars, carcass composition did not differ with triptorelin treatment.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeCarcass composition
Study
pign = 38
Young boars
Comparator
Saline
Outcome group
Body composition · Musculoskeletal
Studied dose
Dose not stated
Source sentences
Summary
The GnRH-agonist did not influence the carcass composition of treated boars.
3 context sentences(design, population, supporting numbers)
Summary · context
A study was designed to determine the effects of triptorelin (Decapeptyl C.R.), a GnRH-agonist in a depot formulation, on androst-16-en-3-one (androstenone), LH, oestradiol and testosterone and on carcass composition and muscle structure in boars.
Summary · context
Treatment with this highly potent GnRH analog ensured peptide release for 4 weeks when given to 18 animals at 135 days of age (group 1).
Summary · context
Control animals (n = 20, group 2) received a saline injection.
Report a problemFND-0961518109
07AnimalAnimal study (in vivo)Efficacy outcome
In boars, muscle meat percentage did not differ significantly between triptorelin and controls.
In plain wordsIn boars, muscle meat percentage did not differ significantly between triptorelin and controls.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
No significant changeMuscle meat percentage
Study
pign = 38
Young boars
Comparator
Saline
Outcome group
Body composition · Musculoskeletal
Studied dose
Dose not stated
Measurements
Muscle meat
51.39%
treated
Muscle meat
50.5%
control
Source sentences
Summary
The muscle meat percentage was not significantly altered in the experimental group (51.39 vs. 50.50%).
3 context sentences(design, population, supporting numbers)
Summary · context
A study was designed to determine the effects of triptorelin (Decapeptyl C.R.), a GnRH-agonist in a depot formulation, on androst-16-en-3-one (androstenone), LH, oestradiol and testosterone and on carcass composition and muscle structure in boars.
Summary · context
Treatment with this highly potent GnRH analog ensured peptide release for 4 weeks when given to 18 animals at 135 days of age (group 1).
Summary · context
Control animals (n = 20, group 2) received a saline injection.
Report a problemFND-0961518110
08AnimalAnimal study (in vivo)Efficacy outcome
In boars, triptorelin increased LH for one day, followed by a return to baseline.
In plain wordsIn boars, LH increased for one day after triptorelin and then returned to baseline.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
MixedLH time course
Study
pign = 18
Young boars
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
Dose not stated
Source sentences
Summary
The treatment of boars with triptorelin increased concentrations of LH, oestradiol-17 beta, and testosterone for one day, followed by a decrease to base-line concentrations.
3 context sentences(design, population, supporting numbers)
Summary · context
A study was designed to determine the effects of triptorelin (Decapeptyl C.R.), a GnRH-agonist in a depot formulation, on androst-16-en-3-one (androstenone), LH, oestradiol and testosterone and on carcass composition and muscle structure in boars.
Summary · context
Treatment with this highly potent GnRH analog ensured peptide release for 4 weeks when given to 18 animals at 135 days of age (group 1).
Summary · context
Control animals (n = 20, group 2) received a saline injection.
Report a problemFND-0961518101
09AnimalAnimal study (in vivo)Efficacy outcome
In boars, triptorelin increased oestradiol for one day, followed by a return to baseline.
In plain wordsIn boars, oestradiol increased for one day after triptorelin and then returned to baseline.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
MixedOestradiol time course
Study
pign = 18
Young boars
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
Dose not stated
Source sentences
Summary
The treatment of boars with triptorelin increased concentrations of LH, oestradiol-17 beta, and testosterone for one day, followed by a decrease to base-line concentrations.
3 context sentences(design, population, supporting numbers)
Summary · context
A study was designed to determine the effects of triptorelin (Decapeptyl C.R.), a GnRH-agonist in a depot formulation, on androst-16-en-3-one (androstenone), LH, oestradiol and testosterone and on carcass composition and muscle structure in boars.
Summary · context
Treatment with this highly potent GnRH analog ensured peptide release for 4 weeks when given to 18 animals at 135 days of age (group 1).
Summary · context
Control animals (n = 20, group 2) received a saline injection.
Report a problemFND-0961518102
10AnimalAnimal study (in vivo)Efficacy outcome
In boars, triptorelin increased testosterone for one day, followed by a return to baseline.
In plain wordsIn boars, testosterone increased for one day after triptorelin and then returned to baseline.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
MixedTestosterone time course
Study
pign = 18
Young boars
Outcome group
Sex hormones and fertility · Reproductive and sexual health
Studied dose
Dose not stated
Source sentences
Summary
The treatment of boars with triptorelin increased concentrations of LH, oestradiol-17 beta, and testosterone for one day, followed by a decrease to base-line concentrations.
3 context sentences(design, population, supporting numbers)
Summary · context
A study was designed to determine the effects of triptorelin (Decapeptyl C.R.), a GnRH-agonist in a depot formulation, on androst-16-en-3-one (androstenone), LH, oestradiol and testosterone and on carcass composition and muscle structure in boars.
Summary · context
Treatment with this highly potent GnRH analog ensured peptide release for 4 weeks when given to 18 animals at 135 days of age (group 1).
Summary · context
Control animals (n = 20, group 2) received a saline injection.
Report a problemFND-0961518103

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
22 Oct 2026, 02:26 UTC
Study results updated
Version 1
21 Oct 2026, 18:59 UTC
First added · source update from Europe PMC

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