Postmenopausal virilization in a woman with gonadotropin dependent ovarian hyperthecosis.

Manieri C, Di Bisceglie C, Fornengo R, Grosso T, Zumpano E, Calvo F, Berardengo E, Volante M, Papotti M

Journal of endocrinological investigation1 Feb 1998Cited by 14 (Europe PMC)

PMID9585388DOI10.1007/bf03350327PepBankPUB-09585388

Publisher page PubMedAsk about this study

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. 5 results from people.

01HumanCase report or seriesEfficacy outcome
In a woman with ovarian hyperthecosis, total testosterone normalized after triptorelin.
In plain wordsIn a woman with ovarian hyperthecosis, triptorelin reduced total testosterone to normal levels.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseTotal testosterone normalization
Study
n = 1
Outcome group
Sex hormones and fertility · Endocrine and hormones
Studied dose
Dose not stated · intramuscular · 18 daysAs given in this study (human).
Source sentences
Summary
TT, FT and 17-OHP were normalized, and FSH and LH fell to premenopausal levels on 18th day after a single i.m. injection of the GnRH analogue (GnRHa), triptorelin.
1 context sentence(design, population, supporting numbers)
Summary · context
We report a case of a 66-yr-old woman with progressive hair balding, hirsutism and virilization.
Report a problemFND-0958538801
02HumanCase report or seriesEfficacy outcome
In a woman with ovarian hyperthecosis, free testosterone normalized after triptorelin.
In plain wordsIn a woman with ovarian hyperthecosis, triptorelin reduced free testosterone to normal levels.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseFree testosterone normalization
Study
n = 1
Outcome group
Sex hormones and fertility · Endocrine and hormones
Studied dose
Dose not stated · intramuscular · 18 daysAs given in this study (human).
Source sentences
Summary
TT, FT and 17-OHP were normalized, and FSH and LH fell to premenopausal levels on 18th day after a single i.m. injection of the GnRH analogue (GnRHa), triptorelin.
1 context sentence(design, population, supporting numbers)
Summary · context
We report a case of a 66-yr-old woman with progressive hair balding, hirsutism and virilization.
Report a problemFND-0958538802
03HumanCase report or seriesEfficacy outcome
In a woman with ovarian hyperthecosis, 17-hydroxyprogesterone normalized after triptorelin.
In plain wordsIn a woman with ovarian hyperthecosis, triptorelin reduced 17-hydroxyprogesterone to normal levels.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
Decrease17-hydroxyprogesterone normalization
Study
n = 1
Outcome group
Sex hormones and fertility · Endocrine and hormones
Studied dose
Dose not stated · intramuscular · 18 daysAs given in this study (human).
Source sentences
Summary
TT, FT and 17-OHP were normalized, and FSH and LH fell to premenopausal levels on 18th day after a single i.m. injection of the GnRH analogue (GnRHa), triptorelin.
2 context sentences(design, population, supporting numbers)
Summary · context
Gonadotropins and estradiol levels were in the postmenopausal range; total testosterone (TT), free testosterone (FT) and 17-hydroxyprogesterone (17-OHP) were elevated with dehydroepiandrosterone sulphate, androstendione and cortisol serum levels in the normal range, as 24-hr free urinary cortisol.
Summary · context
We report a case of a 66-yr-old woman with progressive hair balding, hirsutism and virilization.
Report a problemFND-0958538803
04HumanCase report or seriesEfficacy outcome
In a woman with ovarian hyperthecosis, FSH fell to premenopausal levels after triptorelin.
In plain wordsIn a woman with ovarian hyperthecosis, FSH decreased after triptorelin.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseFSH
Study
n = 1
Outcome group
Sex hormones and fertility · Endocrine and hormones
Studied dose
Dose not stated · intramuscular · single injectionAs given in this study (human).
Source sentences
Summary
TT, FT and 17-OHP were normalized, and FSH and LH fell to premenopausal levels on 18th day after a single i.m. injection of the GnRH analogue (GnRHa), triptorelin.
1 context sentence(design, population, supporting numbers)
Summary · context
We report a case of a 66-yr-old woman with progressive hair balding, hirsutism and virilization.
Report a problemFND-0958538804
05HumanCase report or seriesEfficacy outcome
In a woman with ovarian hyperthecosis, LH fell to premenopausal levels after triptorelin.
In plain wordsIn a woman with ovarian hyperthecosis, LH decreased after triptorelin.
Peptide
Triptorelin (Trelstar, Decapeptyl)
Outcome
DecreaseLH
Study
n = 1
Outcome group
Sex hormones and fertility · Endocrine and hormones
Studied dose
Dose not stated · intramuscular · single injectionAs given in this study (human).
Source sentences
Summary
TT, FT and 17-OHP were normalized, and FSH and LH fell to premenopausal levels on 18th day after a single i.m. injection of the GnRH analogue (GnRHa), triptorelin.
1 context sentence(design, population, supporting numbers)
Summary · context
We report a case of a 66-yr-old woman with progressive hair balding, hirsutism and virilization.
Report a problemFND-0958538805

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
22 Oct 2026, 02:26 UTC
Study results updated
Version 1
21 Oct 2026, 18:59 UTC
First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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