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Study · Ex vivo tissue · chick · 1997

3 results

[The effect of brain peptides on nerve tissue cells in vitro].

Khavinson VKh, Morozov VG, Chalisova NI, Okulov VB

Tsitologiia1 Jan 1997Cited by 1 (Europe PMC)

PMID9490497 (opens in a new tab)PepBankPUB-09490497
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01LabEx vivo tissueActivity measurement

    In chick embryo dorsal root ganglion cultures, cortexin increased neurite outgrowth compared with control.

    In plain wordsIn lab tests, cortexin increased nerve process growth in chick embryo ganglion cultures compared with control.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    IncreaseDorsal root ganglion neurite outgrowth
    Study

    chickn: not reported in source

    embryonic organotypic neural tissue cultures
    Comparator
    Control
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    20 and 100 ng/mlAs given in this study (chick).

    Source sentences

    Summary
    Cortexin in concentrations of 20 and 100 ng/ml is active, inducing a more intensive neurite outgrowth in DRG, compared to the control.
    1 context sentence
    Summary · context
    The effect of cortexin and epithalamin on the cell growth rate was investigated in the organotypic tissue culture of dorsal root ganglia (DRG), and of cortex and subcortical structures of 10-11-day old chick embryos.
  2. 02LabEx vivo tissueActivity measurement

    In chick embryo cortex tissue cultures, cortexin showed growth-stimulating activity.

    In plain wordsIn lab tests, cortexin showed growth-stimulating activity in chick embryo cortex tissue cultures.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    IncreaseCortex tissue culture growth
    Study

    chickn: not reported in source

    embryonic organotypic neural tissue cultures
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    100 ng/mlAs given in this study (chick).

    Source sentences

    Summary
    Cortexin (100 ng/ml) was active in the cortex tissue culture, but inhibited the neurite growth in the subcortical structures culture.
    1 context sentence
    Summary · context
    The effect of cortexin and epithalamin on the cell growth rate was investigated in the organotypic tissue culture of dorsal root ganglia (DRG), and of cortex and subcortical structures of 10-11-day old chick embryos.
  3. 03LabEx vivo tissueActivity measurement

    In chick embryo subcortical tissue cultures, cortexin inhibited neurite growth.

    In plain wordsIn lab tests, cortexin inhibited nerve process growth in chick embryo subcortical tissue cultures.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    DecreaseSubcortical neurite growth
    Study

    chickn: not reported in source

    embryonic organotypic neural tissue cultures
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    100 ng/mlAs given in this study (chick).

    Source sentences

    Summary
    Cortexin (100 ng/ml) was active in the cortex tissue culture, but inhibited the neurite growth in the subcortical structures culture.
    1 context sentence
    Summary · context
    The effect of cortexin and epithalamin on the cell growth rate was investigated in the organotypic tissue culture of dorsal root ganglia (DRG), and of cortex and subcortical structures of 10-11-day old chick embryos.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:25 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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