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Study · Non-randomized trial · 1997

3 results

Circulating leptin concentrations in women with hirsutism.

Escobar-Morreale HF, Serrano-Gotarredona J, Varela C, García-Robles R, Sancho JM

Fertility and sterility1 Nov 1997Cited by 28 (Europe PMC)

PMID9389823 (opens in a new tab)DOI10.1016/s0015-0282(97)00336-1 (opens in a new tab)PepBankPUB-09389823
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanNon-randomized trialMechanism

    In women studied during gonadal stimulation, leptin increased from baseline on day 1 after triptorelin.

    In plain wordsIn women, leptin increased from baseline on day 1 after triptorelin.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    IncreaseLeptin at day one
    Study

    n: not reported in source

    Comparator
    Baseline
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    3.75 mg single dose · intramuscularAs given in this study (human).

    Source sentences

    Summary
    Leptin levels increased on day 1 compared with baseline and then decreased to baseline by day 21.
    2 context sentences
    Summary · context
    Thirty-three hirsute women and 11 healthy female controls.
    Summary · context
    Serum samples were obtained at baseline and on day 1 (gonadal stimulation) and day 21 (gonadal suppression) after the IM injection of a single 3.75-mg dose of triptorelin.
  2. 02HumanNon-randomized trialMechanism

    In women studied during gonadal suppression, leptin returned to baseline by day 21 after triptorelin.

    In plain wordsIn women, leptin returned to baseline by day 21 after triptorelin.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    No significant changeLeptin at day twenty-one
    Study

    n: not reported in source

    Comparator
    Baseline
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones
    Studied dose
    3.75 mg single dose · intramuscularAs given in this study (human).

    Source sentences

    Summary
    Leptin levels increased on day 1 compared with baseline and then decreased to baseline by day 21.
    2 context sentences
    Summary · context
    Thirty-three hirsute women and 11 healthy female controls.
    Summary · context
    Serum samples were obtained at baseline and on day 1 (gonadal stimulation) and day 21 (gonadal suppression) after the IM injection of a single 3.75-mg dose of triptorelin.

Studies that did not test the peptide alone1

In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Triptorelin (Trelstar, Decapeptyl).

  1. 03HumanNot a test of Triptorelin (Trelstar, Decapeptyl) aloneNon-randomized trialMechanism

    In hirsute women, after obesity adjustment, leptin stayed higher than in healthy controls only on day 1 after a single triptorelin injection.

    In plain wordsAfter obesity adjustment, hirsute women had higher leptin than healthy controls only on day 1 after a triptorelin injection.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    IncreaseLeptin after obesity adjustment
    Study

    n: not reported in source

    Comparator
    Healthy female controls
    Outcome group
    Receptor activity and mechanism · Endocrine and hormones

    Source sentences

    Summary
    When the effect of obesity on these results was removed by analysis of covariance and partial correlation analysis, leptin levels remained elevated only on day 1
    2 context sentences
    Summary · context
    Thirty-three hirsute women and 11 healthy female controls.
    Summary · context
    Serum samples were obtained at baseline and on day 1 (gonadal stimulation) and day 21 (gonadal suppression) after the IM injection of a single 3.75-mg dose of triptorelin.

    In this study, Triptorelin (Trelstar, Decapeptyl) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Triptorelin (Trelstar, Decapeptyl).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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