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Study · Not a test of the peptide alone · 1997

2 results

Beta-thymosins from marine invertebrates: primary structure and interaction with actin.

Safer D, Chowrashi PK

Cell motility and the cytoskeleton1 Jan 1997Cited by 33 (Europe PMC)

PMID9331220 (opens in a new tab)DOI10.1002/(sici)1097-0169(1997)38:2<163::aid-cm5>3.0.co;2-8 (opens in a new tab)PepBankPUB-09331220
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin beta-4 (human).

  1. 01LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cell-free)Activity measurement

    In cell-free assays with rabbit muscle actin, the sea urchin peptide needed about twice the concentration of thymosin beta‑4 to inhibit actin polymerization or nucleotide exchange equally.

    In plain wordsIn lab tests, a sea urchin peptide bound actin more weakly than thymosin beta‑4. It needed about twice the concentration for the same effect.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableActin inhibition by sea urchin peptide compared with thymosin beta 4
    Study

    n: not reported in source

    Rabbit muscle actin, cell-free
    Comparator
    Thymosin beta 4
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Source sentences

    Summary
    The affinity of the sea urchin peptide for rabbit muscle actin is apparently lower than that of thymosin beta4, since about twice the concentration of sea urchin peptide is required to give inhibition of actin polymerization or nucleotide exchange equivalent to thymosin beta4.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

  2. 02Computer modelNot a test of Thymosin beta-4 (human) aloneIn silicoOther

    The scallop and sea urchin beta-thymosins are 75% identical to residues 1-40 of thymosin beta‑4.

    In plain wordsA sequence comparison found that two marine invertebrate peptides are 75% identical to the first 40 residues of thymosin beta‑4.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableSequence identity of scallop and sea urchin beta-thymosins to thymosin beta 4
    Study

    n: not reported in source

    Sequence comparison
    Outcome group
    Receptor activity and mechanism · Pharmacology

    Measurements

    sequence identity
    75%
    residues 1-40 of thymosin beta 4

    Source sentences

    Summary
    The sequences of the scallop and sea urchin beta-thymosins are 80% identical to each other, 75% identical to residues 1-40 of thymosin beta4, and 72-80% identical to residues 1-40 of other vertebrate beta-thymosins.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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