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Study · Non-randomized trial · 1997

2 results

A comparison of glucagon and glucose in prehospital hypoglycaemia.

Howell MA, Guly HR

Journal of accident & emergency medicine1 Jan 1997Cited by 23 (Europe PMC)

PMID9023620 (opens in a new tab)PMCIDPMC1342840 (opens in a new tab)DOI10.1136/emj.14.1.30 (opens in a new tab)PepBankPUB-09023620
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In adults with prehospital hypoglycaemia, median recovery was significantly longer with the glucagon protocol: 28 versus 11 minutes with the glucose protocol.

    In plain wordsIn adults with prehospital hypoglycaemia, recovery took longer with the glucagon protocol than the glucose protocol.

    Peptide
    Glucagon
    Outcome
    IncreaseTime to full orientation
    Study

    n: not reported in source

    Comparator
    Intravenous glucose protocol with rescue glucagon
    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    1 mg · intramuscularAs given in this study (human).

    Measurements

    Median recovery time
    28 minutes
    glucagon protocol; 95% confidence interval 18 to 49 minutes
    Median recovery time
    11 minutes
    glucose protocol; 95% confidence interval 8 to 19 minutes

    Source sentences

    Summary
    In the second part of the study the median duration from diagnosis to full orientation (Glasgow coma score 15) was 28 minutes (95% confidence interval 18 to 49 minutes) in phase 1 and 11 minutes (95% confidence interval 8 to 19 minutes) in phase 2.
    2 context sentences
    Summary · context
    This difference is statistically significant (P < 0.005).
    Summary · context
    In the second part, two protocols for treating prehospital hypoglycaemia were studied. In phase 1, intramuscular glucagon 1 mg was used. In phase 2, intravenous glucose 25 g was used; if intravenous access was not possible, intramuscular glucagon was given.
  2. 02HumanNon-randomized trialEfficacy outcome

    In adults with prehospital hypoglycaemia, on-scene times did not differ significantly between the glucagon and glucose protocols.

    In plain wordsIn adults with prehospital hypoglycaemia, on-scene times did not differ significantly between the glucagon and glucose protocols.

    Peptide
    Glucagon
    Outcome
    No significant changeOn-scene time
    Study

    n: not reported in source

    Comparator
    Intravenous glucose protocol with rescue glucagon
    Outcome group
    Emergency Care · Metabolic and weight
    Studied dose
    1 mg · intramuscularAs given in this study (human).

    Source sentences

    Summary
    On-scene times were not significantly different.
    1 context sentence
    Summary · context
    In the second part, two protocols for treating prehospital hypoglycaemia were studied. In phase 1, intramuscular glucagon 1 mg was used. In phase 2, intravenous glucose 25 g was used; if intravenous access was not possible, intramuscular glucagon was given.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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