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Study · Measured the body's own peptide · 1996

2 results

Induction of thymosin beta(4) mRNA following focal brain ischemia.

Vartiainen N, Pyykönen I, Hökfelt T, Koistinaho J

Neuroreport1 Jul 1996Cited by 43 (Europe PMC)

PMID8904767 (opens in a new tab)DOI10.1097/00001756-199607080-00017 (opens in a new tab)PepBankPUB-08904767
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    In rats after focal brain ischaemia, thymosin beta‑4 mRNA was strongly up-regulated in the infarcted brain area.

    In plain wordsIn rats after a stroke-like brain injury, natural thymosin beta‑4 messenger RNA rose sharply in the damaged brain area.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseThymosin beta 4 mRNA in infarcted brain area
    Study

    ratn: not reported in source

    focal brain ischaemia
    Outcome group
    Gene expression · Nervous system and cognition

    Source sentences

    Summary
    Here we show by using in situ hybridization that t beta 4 is dramatically up-regulated in the infarcted brain area after focal ischaemia.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    In rats after focal brain ischaemia, moderate induction of thymosin beta‑4 mRNA was found in the perifocal zone, substantia nigra and CA1-CA3 hippocampal pyramidal neurones.

    In plain wordsIn rats after a stroke-like brain injury, natural thymosin beta‑4 messenger RNA also rose moderately in areas around and away from the damage.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseThymosin beta 4 mRNA in perifocal zone, substantia nigra and hippocampus
    Study

    ratn: not reported in source

    focal brain ischaemia
    Outcome group
    Gene expression · Nervous system and cognition

    Source sentences

    Summary
    In addition, moderate t beta 4 induction is detected in the perifocal zone, substantia nigra and CA1-CA3 hippocampal pyramidal neurones.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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