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Study · Not a test of the peptide alone · 1996

4 results

The mouse thymosin beta 4 gene: structure, promoter identification, and chromosome localization.

Li X, Zimmerman A, Copeland NG, Gilbert DJ, Jenkins NA, Yin HL

Genomics1 Mar 1996Cited by 23 (Europe PMC)

PMID8838802 (opens in a new tab)DOI10.1006/geno.1996.0133 (opens in a new tab)PepBankPUB-08838802
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin beta-4 (human).

  1. 01AnimalNot a test of Thymosin beta-4 (human) aloneAnimal study (in vivo)Other

    The mouse thymosin beta‑4 gene locus (Ptmb4) maps to the distal region of the mouse X chromosome, linked to Btk and Gja6.

    In plain wordsIn mice, the thymosin beta‑4 gene sits on the X chromosome near two other genes.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableChromosome location of the mouse T beta 4 gene (Ptmb4)
    Study

    mousen: not reported in source

    mouse genomic DNA
    Outcome group
    Gene expression · Whole body

    Source sentences

    Summary
    The mouse T beta 4 gene locus (Ptmb4) is located by interspecific backcross mapping to the distal region of the mouse X chromosome, linked to Btk and Gja6.
    1 context sentence
    Summary · context
    To determine how T beta 4 gene expression is regulated and how the alternative transcripts are derived, we cloned the mouse T beta 4 gene.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

  2. 02LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cell-free)Other

    There is a single mouse thymosin beta‑4 gene, and the lymphoid-specific transcript is generated by extending the ubiquitous exon 1 with an alternate downstream splice site.

    In plain wordsIn lab tests on mouse DNA, one thymosin beta‑4 gene exists, and immune cells make a longer copy of its message.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableNumber of mouse T beta 4 genes and lymphoid-specific transcript origin
    Study

    mousen: not reported in source

    mouse genomic DNA
    Outcome group
    Gene expression · Whole body

    Source sentences

    Summary
    We established that there is a single mouse T beta 4 gene and found that the lymphoid-specific transcript is generated by extending the ubiquitous exon 1 with an alternate downstream splice site.
    1 context sentence
    Summary · context
    To determine how T beta 4 gene expression is regulated and how the alternative transcripts are derived, we cloned the mouse T beta 4 gene.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

  3. 03LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cell-free)Other

    The transcription start site of the mouse thymosin beta‑4 gene was defined by primer extension, and the 5'-flanking region has characteristics of a promoter.

    In plain wordsIn lab tests on mouse DNA, the start point of thymosin beta‑4 gene reading was found, beside DNA like a gene switch.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableTranscription start site and 5'-flanking region of the T beta 4 gene
    Study

    mousen: not reported in source

    mouse genomic DNA
    Outcome group
    Gene expression · Whole body

    Source sentences

    Summary
    The transcription start site is defined by primer extension analysis, and the 5'-flanking region has many of the characteristics of a promoter.
    1 context sentence
    Summary · context
    To determine how T beta 4 gene expression is regulated and how the alternative transcripts are derived, we cloned the mouse T beta 4 gene.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

  4. 04LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cell-free)Other

    The 5'-flanking region of the mouse thymosin beta‑4 gene is pyrimidine-rich and contains a GC box, an initiator site and consensus transcription factor binding sites.

    In plain wordsIn lab tests on mouse DNA, the DNA next to the thymosin beta‑4 gene holds typical gene-switch parts.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicablePromoter elements of the T beta 4 gene
    Study

    mousen: not reported in source

    mouse genomic DNA
    Outcome group
    Gene expression · Whole body

    Source sentences

    Summary
    It is pyrimidine-rich and contains typical promoter elements, including a GC box, an initiator site, and consensus transcription factor binding sites.
    1 context sentence
    Summary · context
    To determine how T beta 4 gene expression is regulated and how the alternative transcripts are derived, we cloned the mouse T beta 4 gene.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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