Distribution of thymic hormones in thymic tumors and myasthenic thymus.

Wu MH, Low TL

Proceedings of the National Science Council, Republic of China. Part B, Life sciences1 Jan 1996Cited by 3 (Europe PMC)

PMID8765340PepBankPUB-08765340

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Natural levels measured5

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

01HumanEndogenous levelObservational studyOther
In normal thymic tissue of the control group, the concentration of thymosin beta‑4 decreased with age.
In plain wordsIn people, natural thymosin beta‑4 in normal thymus tissue was lower at older ages.
Peptide
Thymosin beta-4 (human)
Outcome
DecreaseAge-related thymosin beta 4 tissue concentration in normal thymus
Study
n = 25
Outcome group
Gene expression · Immune and inflammation
Source sentences
Summary
It was found that in the control group the concentrations (microgram/g tissue) of prothymosin alpha and thymosin beta 4 decreased with age, and that the ranges were from 171 micrograms/g to trace and from 243 micrograms/g to trace, respectively.
2 context sentences(design, population, supporting numbers)
Summary · context
A total of forty four thymus or thymic tumor tissues were obtained from patients who underwent thoracic operation.
Summary · context
These tissues consisted of a control group (n = 25) and three study groups including a thymoma group (N = 8), thymic carcinoma group (n = 3) and myasthenic thymus group (n = 8).
This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0876534001
02HumanEndogenous levelObservational studyOther
Thymosin beta‑4 amounts in normal thymic tissue were highest at puberty and then gradually decreased, with only trace amounts at age 60.
In plain wordsIn people, natural thymosin beta‑4 in thymus tissue peaked at puberty and was only a trace at age 60.
Peptide
Thymosin beta-4 (human)
Outcome
DecreaseThymosin beta 4 tissue concentration across ages (puberty to age 60)
Study
n = 25
Outcome group
Gene expression · Immune and inflammation
Source sentences
Summary
The amounts were highest at puberty and then gradually decreased, and only trace amounts of both polypeptides were present at age 60.
2 context sentences(design, population, supporting numbers)
Summary · context
A total of forty four thymus or thymic tumor tissues were obtained from patients who underwent thoracic operation.
Summary · context
These tissues consisted of a control group (n = 25) and three study groups including a thymoma group (N = 8), thymic carcinoma group (n = 3) and myasthenic thymus group (n = 8).
This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0876534002
03HumanEndogenous levelObservational studyOther
Thymic hormone contents, including thymosin beta‑4, increased significantly in invasive or non-invasive thymoma compared with age-related normal thymus.
In plain wordsIn people, natural thymosin beta‑4 was higher in thymoma tissue than in normal thymus tissue of the same age.
Peptide
Thymosin beta-4 (human)
Outcome
IncreaseThymosin beta 4 content in thymoma tissue
Study
n = 8
Comparator
Age-related normal thymus tissue
Outcome group
Gene expression · Immune and inflammation
Source sentences
Summary
Our results indicated that the contents of thymic hormones significantly increased in the tissues of invasive or non-invasive thymoma,
2 context sentences(design, population, supporting numbers)
Summary · context
A total of forty four thymus or thymic tumor tissues were obtained from patients who underwent thoracic operation.
Summary · context
These tissues consisted of a control group (n = 25) and three study groups including a thymoma group (N = 8), thymic carcinoma group (n = 3) and myasthenic thymus group (n = 8).
This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0876534003
04HumanEndogenous levelObservational studyOther
Thymic hormone contents, including thymosin beta‑4, were not significantly changed in myasthenic thymus compared with age-related normal thymus.
In plain wordsIn people, natural thymosin beta‑4 in myasthenic thymus did not differ clearly from normal thymus tissue of the same age.
Peptide
Thymosin beta-4 (human)
Outcome
No significant changeThymosin beta 4 content in myasthenic thymus
Study
n = 8
Comparator
Age-related normal thymus tissue
Outcome group
Gene expression · Immune and inflammation
Source sentences
Summary
Our results indicated that the contents of thymic hormones significantly increased in the tissues of invasive or non-invasive thymoma, decreased in thymic carcinoma, and were not significantly changed in myasthenic thymus as compared with those of the age-related normal thymus tissues.
2 context sentences(design, population, supporting numbers)
Summary · context
A total of forty four thymus or thymic tumor tissues were obtained from patients who underwent thoracic operation.
Summary · context
These tissues consisted of a control group (n = 25) and three study groups including a thymoma group (N = 8), thymic carcinoma group (n = 3) and myasthenic thymus group (n = 8).
This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0876534005
05HumanEndogenous levelObservational studyOther
Thymic hormone contents, including thymosin beta‑4, decreased in thymic carcinoma compared with age-related normal thymus.
In plain wordsIn people, natural thymosin beta‑4 was lower in thymic carcinoma tissue than in normal thymus tissue of the same age.
Peptide
Thymosin beta-4 (human)
Outcome
DecreaseThymosin beta 4 content in thymic carcinoma tissue
Study
n = 3
Comparator
Age-related normal thymus tissue
Outcome group
Gene expression · Immune and inflammation
Source sentences
Summary
Our results indicated that the contents of thymic hormones significantly increased in the tissues of invasive or non-invasive thymoma, decreased in thymic carcinoma, and were not significantly changed in myasthenic thymus as compared with those of the age-related normal thymus tissues.
2 context sentences(design, population, supporting numbers)
Summary · context
A total of forty four thymus or thymic tumor tissues were obtained from patients who underwent thoracic operation.
Summary · context
These tissues consisted of a control group (n = 25) and three study groups including a thymoma group (N = 8), thymic carcinoma group (n = 3) and myasthenic thymus group (n = 8).
This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.
Report a problemFND-0876534004

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

Version 2Current
13 Oct 2026, 01:52 UTC
Study results updated
Version 1
12 Oct 2026, 18:17 UTC
First added · source update from Europe PMC

Subjects

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