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Study · Randomized controlled trial · n = 32 · 1996

2 results

Short term pituitary desensitization: effects of different doses of the gonadotrophin-releasing hormone agonist triptorelin.

Broekmans FJ, Hompes PG, Lambalk CB, Schoute E, Broeders A, Schoemaker J

Human reproduction (Oxford, England)1 Jan 1996Cited by 22 (Europe PMC)

PMID8671156 (opens in a new tab)DOI10.1093/oxfordjournals.humrep.a019034 (opens in a new tab)PepBankPUB-08671156
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanRandomized controlled trialMechanism

    In cycling women, pituitary desensitization during triptorelin treatment depended on dose.

    In plain wordsIn women, pituitary suppression during triptorelin treatment depended on dose.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Direction not reportedPituitary desensitization
    Study

    n = 32

    Comparator
    Different triptorelin doses
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Both pituitary desensitization during and pituitary recovery after agonist treatment, expressed as the LH response to exogenous GnRH, appeared to be dose dependent.
    2 context sentences
    Summary · context
    This double-blind randomized study was undertaken to assess the effect of four different doses to triptorelin on the degree of desensitization of the pituitary, and the recovery time of pituitary function after withdrawal of the agonist.
    Summary · context
    Sixty-six regularly cycling women were allocated to a treatment group (n = 32) and a control group (n = 34).
  2. 02HumanRandomized controlled trialMechanism

    In cycling women, pituitary recovery after triptorelin withdrawal depended on dose.

    In plain wordsIn women, pituitary recovery after triptorelin withdrawal depended on dose.

    Peptide
    Triptorelin (Trelstar, Decapeptyl)
    Outcome
    Direction not reportedPituitary recovery
    Study

    n = 32

    Comparator
    Different triptorelin doses
    Outcome group
    Sex hormones and fertility · Endocrine and hormones
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Both pituitary desensitization during and pituitary recovery after agonist treatment, expressed as the LH response to exogenous GnRH, appeared to be dose dependent.
    2 context sentences
    Summary · context
    This double-blind randomized study was undertaken to assess the effect of four different doses to triptorelin on the degree of desensitization of the pituitary, and the recovery time of pituitary function after withdrawal of the agonist.
    Summary · context
    Sixty-six regularly cycling women were allocated to a treatment group (n = 32) and a control group (n = 34).

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:26 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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