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Study · Measured the body's own peptide · 1996

5 results

High levels of mouse thymosin beta4 mRNA in differentiating P19 embryonic cells and during development of cardiovascular tissues.

Gómez-Márquez J, Franco del Amo F, Carpintero P, Anadón R

Biochimica et biophysica acta1 May 1996Cited by 32 (Europe PMC)

PMID8634336 (opens in a new tab)DOI10.1016/0167-4781(96)00003-6 (opens in a new tab)PepBankPUB-08634336
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

No result from this study comes from a test of the peptide.

Natural levels measured5

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    The induction of thymosin beta4 mRNA in P19 cells was confirmed by in situ hybridization in early mouse postimplantation embryos.

    In plain wordsIn mouse embryos, the body's own thymosin beta4 messenger RNA was found, which agreed with the cell results.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseConfirmation of Tbeta4 mRNA induction by in situ hybridization
    Study

    mousen: not reported in source

    early postimplantation embryos
    Outcome group
    Gene expression · Whole body

    Source sentences

    Summary
    The induction of Tbeta4, mRNA in P19 cells was confirmed by in situ hybridization analysis of early mouse postimplantation embryos.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    An important in situ hybridization signal for thymosin beta4 mRNA was observed in several areas of the mouse embryo, especially in blood vessels and heart tissues.

    In plain wordsIn mouse embryos, the body's own thymosin beta4 messenger RNA was strong in blood vessels and heart tissue.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseTbeta4 hybridization signal in blood vessels and heart tissue
    Study

    mousen: not reported in source

    early postimplantation embryos
    Outcome group
    Gene expression · Cardiovascular

    Source sentences

    Summary
    Noteworthy, we observed an important hybridization signal in several areas of the embryo specially in blood vessels and in heart tissues, suggesting a role for this peptide in angiogenesis.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelIn vitro (cells)Other

    The mRNA encoding thymosin beta4 is present in mouse embryonic stem cells.

    In plain wordsIn mouse cells, the cells' own thymosin beta4 messenger RNA was present in embryonic stem cells.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableTbeta4 mRNA in mouse embryonic stem cells
    Study

    mousen: not reported in source

    mouse embryonic stem cells
    Outcome group
    Gene expression · Whole body

    Source sentences

    Summary
    we report the presence of the mRNA encoding for Tbeta4 in mouse embryonic stem cells

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  4. 04LabEndogenous levelIn vitro (cells)Other

    Thymosin beta4 mRNA was induced in P19 embryonal cells stimulated to differentiate into ectodermal-like cells (neurons and glia).

    In plain wordsIn mouse cells, the cells' own thymosin beta4 messenger RNA rose when cells turned into nerve-like cells.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseTbeta4 mRNA induction on ectodermal-like differentiation
    Study

    mousen: not reported in source

    P19 embryonal cells
    Outcome group
    Gene expression · Nervous system and cognition

    Source sentences

    Summary
    its induction in P1 9 embryonal cells stimulated to differentiate into ectodermal-like (neurons and glia)

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  5. 05LabEndogenous levelIn vitro (cells)Other

    Thymosin beta4 mRNA was induced in P19 embryonal cells stimulated to differentiate into mesodermal-like cells (cardiac and skeletal muscle).

    In plain wordsIn mouse cells, the cells' own thymosin beta4 messenger RNA rose when cells turned into heart-like or muscle-like cells.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseTbeta4 mRNA induction on mesodermal-like differentiation
    Study

    mousen: not reported in source

    P19 embryonal cells
    Outcome group
    Gene expression · Whole body

    Source sentences

    Summary
    its induction in P1 9 embryonal cells stimulated to differentiate into ectodermal-like (neurons and glia) or mesodermal-like cells (cardiac and skeletal muscle).

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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