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Study · Not a test of the peptide alone · 1995

2 results

High-performance liquid chromatographic assay for Melanotan-1 ([Nle4-DPhe7]alpha-melanocyte-stimulating hormone) in biological matrices.

Surendran N, Ugwu SO, Sterling EJ, Blanchard J

Journal of chromatography. B, Biomedical applications1 Aug 1995Cited by 9 (Europe PMC)

PMID8548013 (opens in a new tab)DOI10.1016/0378-4347(95)00177-8 (opens in a new tab)PepBankPUB-08548013
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Melanotan I (afamelanotide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Melanotan I (afamelanotide).

  1. 01LabNot a test of Melanotan I (afamelanotide) aloneOther designOther

    The HPLC assay for Melanotan-1 gave linear standard curves over 100-1000 ng/ml.

    In plain wordsA lab test method measured Melanotan-1 reliably across 100-1000 ng/ml.

    Peptide
    Melanotan I (afamelanotide)
    Outcome
    Not applicableHPLC assay linearity
    Study

    n: not reported in source

    HPLC assay in cell culture transport media and human plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Linear range
    100 to 1000 ng/ml
    HPLC standard curves

    Source sentences

    Summary
    Standard curves (n = 5) were linear over the concentration range 100-1000 ng/ml.
    1 context sentence
    Summary · context
    The overall objective of this research was to develop a sensitive, specific, and stability-indicating HPLC assay for the determination of the [Nle4-DPhe7]alpha-melanocyte-stimulating hormone analog known as Melanotan-1 (MT-1) in biological matrices, i.e., cell culture transport media and human plasma.

    In this study, Melanotan I (afamelanotide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Melanotan I (afamelanotide).

  2. 02LabNot a test of Melanotan I (afamelanotide) aloneOther designOther

    The HPLC assay for Melanotan-1 had precision, accuracy, and intra- and inter-day variations that were good, with C.V.s typically within 8.7% above 100 ng/ml.

    In plain wordsA lab test method for Melanotan-1 gave repeatable results, with variation typically within 8.7% above 100 ng/ml.

    Peptide
    Melanotan I (afamelanotide)
    Outcome
    Not applicableHPLC assay precision and accuracy
    Study

    n: not reported in source

    HPLC assay in cell culture transport media and human plasma
    Outcome group
    Analytical methods and detection · Pharmacology

    Measurements

    Coefficient of variation
    ≤ 8.7%
    concentrations above 100 ng/ml

    Source sentences

    Summary
    The precision, accuracy, intra- and inter-day variations were good with C.V.s typically within 8.7% for concentrations greater than 100 ng/ml.
    1 context sentence
    Summary · context
    The overall objective of this research was to develop a sensitive, specific, and stability-indicating HPLC assay for the determination of the [Nle4-DPhe7]alpha-melanocyte-stimulating hormone analog known as Melanotan-1 (MT-1) in biological matrices, i.e., cell culture transport media and human plasma.

    In this study, Melanotan I (afamelanotide) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Melanotan I (afamelanotide).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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