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Study · Not a test of the peptide alone · 1993

2 results

[Changes in the morphology of the thymus and spleen of healthy mice in combined exposure to nitrosomethylurea and immunomodulators].

Potapov IuN, Pashkova VS, Krutova TV, Khaleev DV

Izvestiia Akademii nauk. Seriia biologicheskaia1 May 1993

PMID8518725 (opens in a new tab)PepBankPUB-08518725
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymalin.

  1. 01AnimalNot a test of Thymalin aloneAnimal study (in vivo)Safety outcome

    In healthy mice, NMU combined with pooled immunomodulators including thymalin did not change acute NMU toxicity.

    In plain wordsIn mice, NMU with pooled immunomodulators including thymalin did not change acute toxicity compared with NMU alone.

    Peptide
    Thymalin
    Outcome
    No significant changeAcute NMU toxicity
    Study

    mousen: not reported in source

    Healthy mice exposed to nitrosomethylurea
    Comparator
    NMU alone
    Outcome group
    Adverse events · Immune and inflammation

    Source sentences

    Summary
    The combined use of NMU and of immunomodulators did not change the NMU acute toxicity but reduced its distant effects.
    1 context sentence
    Summary · context
    Changes in the histological structure of thymus and spleen, changes in the area of immune organs occupied by T- and B-lymphocytes and their proliferative activity were studied after the separate and combined treatment of the healthy mice with nitrosomethylurea (NMU), thymalin and Reaferon.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  2. 02AnimalNot a test of Thymalin aloneAnimal study (in vivo)Safety outcome

    In healthy mice, NMU combined with pooled immunomodulators including thymalin reduced distant NMU effects.

    In plain wordsIn mice, NMU with pooled immunomodulators including thymalin reduced distant effects compared with NMU alone.

    Peptide
    Thymalin
    Outcome
    DecreaseDistant NMU effects
    Study

    mousen: not reported in source

    Healthy mice exposed to nitrosomethylurea
    Comparator
    NMU alone
    Outcome group
    Adverse events · Immune and inflammation

    Source sentences

    Summary
    The combined use of NMU and of immunomodulators did not change the NMU acute toxicity but reduced its distant effects.
    1 context sentence
    Summary · context
    Changes in the histological structure of thymus and spleen, changes in the area of immune organs occupied by T- and B-lymphocytes and their proliferative activity were studied after the separate and combined treatment of the healthy mice with nitrosomethylurea (NMU), thymalin and Reaferon.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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