Skip to content

Study · Measured the body's own peptide · 1993

3 results

Transcript levels of thymosin beta 4, an actin-sequestering peptide, in cell proliferation.

Otero A, Bustelo XR, Pichel JG, Freire M, Gómez-Márquez J

Biochimica et biophysica acta1 Mar 1993Cited by 17 (Europe PMC)

PMID8452879 (opens in a new tab)DOI10.1016/0167-4889(93)90177-q (opens in a new tab)PepBankPUB-08452879
Publisher pagePubMedAsk about this study
Jump to 3 results

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueMechanism

    In rat thymocytes and hepatocytes, the body's own thymosin beta‑4 mRNA was found in all stages of the cell cycle.

    In plain wordsIn rat cells, the body's own thymosin beta‑4 messenger RNA was present in every stage of the cell cycle.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableThymosin beta 4 mRNA across cell cycle stages
    Study

    ratn: not reported in source

    Thymocytes and hepatocytes in the cell cycle
    Outcome group
    Receptor activity and mechanism · Whole body

    Source sentences

    Summary
    beta 4 mRNA was found in all the stages of thymocyte and hepatocyte cell cycle
    1 context sentence
    Summary · context
    In this work, Northern blot analysis was used to study the beta 4 mRNA levels during the cell cycle of rat thymocytes and hepatocytes as well as in human lymphocytes from patients with leukemia.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelEx vivo tissueMechanism

    In rat thymocytes and hepatocytes, the body's own thymosin beta‑4 mRNA increased in the S-phase and stayed raised during the G2 and M phases.

    In plain wordsIn rat cells, the body's own thymosin beta‑4 messenger RNA rose in S-phase and stayed high in later phases.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseThymosin beta 4 mRNA in S-phase
    Study

    ratn: not reported in source

    Thymocytes and hepatocytes in the cell cycle
    Outcome group
    Receptor activity and mechanism · Whole body

    Source sentences

    Summary
    showing an increase in the S-phase which was maintained during the G2 and M phases.
    1 context sentence
    Summary · context
    In this work, Northern blot analysis was used to study the beta 4 mRNA levels during the cell cycle of rat thymocytes and hepatocytes as well as in human lymphocytes from patients with leukemia.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelIn vitro (cells)Mechanism

    In splenic T-cells incubated with concanavalin A, phorbol myristate acetate or the ionophore A23187, the body's own thymosin beta‑4 transcript increased during the S-phase.

    In plain wordsIn splenic T-cells in lab cultures, the body's own thymosin beta‑4 messenger RNA rose in S-phase after stimulation.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseThymosin beta 4 transcript in S-phase after stimulation
    Study

    n: not reported in source

    Splenic T-cells stimulated with concanavalin A, phorbol myristate acetate or A23187
    Outcome group
    Receptor activity and mechanism · Whole body

    Source sentences

    Summary
    Incubation of splenic T-cells with concanavalin A, phorbol myristate acetate or the ionophore A23187 lead to a similar increase of beta 4 transcript during the S-phase.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

PepBank is a research reference. Talk to a doctor before you use any peptide.