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Study · Non-randomized trial · n = 12 · 1993

2 results

Use of desmopressin to prevent bleeding complications in patients treated with aspirin.

Flordal PA, Sahlin S

The British journal of surgery1 Jun 1993Cited by 35 (Europe PMC)

PMID8330156 (opens in a new tab)DOI10.1002/bjs.1800800616 (opens in a new tab)PepBankPUB-08330156
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In aspirin-treated cholecystectomy patients, five postoperative bleeding complications occurred, all in patients without desmopressin (P < 0.05).

    In plain wordsIn aspirin-treated gallbladder surgery patients, bleeding complications occurred only without desmopressin.

    Peptide
    Desmopressin
    Outcome
    DecreasePostoperative bleeding complications
    Study

    n = 12

    Comparator
    No desmopressin
    Outcome group
    Blood Loss · Cardiovascular
    Studied dose
    Dose not stated

    Measurements

    Postoperative bleeding complications
    5 events
    all occurred without desmopressin

    Source sentences

    Summary
    There were five postoperative bleeding complications; all occurred in patients who had not received desmopressin (P < 0.05).
    2 context sentences
    Summary · context
    The effect of the vasopressin analogue desmopressin was studied in 12 patients treated with aspirin who were undergoing cholecystectomy.
    Summary · context
    Desmopressin was given to six of these patients.
  2. 02HumanNon-randomized trialEfficacy outcome

    In aspirin-treated cholecystectomy patients, desmopressin normalized prolonged bleeding time.

    In plain wordsIn aspirin-treated gallbladder surgery patients, desmopressin returned bleeding time to normal.

    Peptide
    Desmopressin
    Outcome
    DecreaseBleeding time
    Study

    n: not reported in source

    Outcome group
    Bleeding and clotting · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The bleeding time was prolonged in aspirin-treated patients and normalized by desmopressin (P < 0.05).
    2 context sentences
    Summary · context
    The effect of the vasopressin analogue desmopressin was studied in 12 patients treated with aspirin who were undergoing cholecystectomy.
    Summary · context
    Desmopressin was given to six of these patients.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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