In horses, natural ACTH gel stimulation failed to distinguish pituitary pars intermedia dysfunction from healthy controls.
In plain wordsIn horses, natural ACTH gel testing did not distinguish affected horses from healthy controls.
- Peptide
- ACTH (corticotropin)
- Outcome
- No significant changeDiagnostic discrimination with natural ACTH gel stimulation
- Study
horsen: not reported in source
Pituitary pars intermedia dysfunction- Comparator
- Healthy control horses
- Outcome group
- Receptor activity and mechanism · Endocrine and hormones
Source sentences
An ACTH stimulation (1 U of natural ACTH gel/kg of body weight, IM) test or a combined dexamethasone suppression test (10 mg, IM) and ACTH stimulation (100 mg of synthetic ACTH, IV) test also failed to distinguish horses with pituitary pars intermedia dysfunction from control horses.
1 context sentence(design, population, supporting numbers)
A variety of tests of pituitary-adrenocortical function were performed on horses with evidence of pituitary pars intermediate dysfunction, and results were compared with those in healthy control horses.
In this study, ACTH (corticotropin) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking ACTH (corticotropin).