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Study · Case report or series · n = 1 · 1994

2 results

Benzocaine-induced methemoglobinemia: report of a severe reaction and review of the literature.

Rodriguez LF, Smolik LM, Zbehlik AJ

The Annals of pharmacotherapy1 May 1994Cited by 65 (Europe PMC)

PMID8069004 (opens in a new tab)DOI10.1177/106002809402800515 (opens in a new tab)PepBankPUB-08069004
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. 2 results from people.

  1. 01HumanCase report or seriesEfficacy outcome

    In a man with benzocaine-induced methemoglobinemia, intravenous methylene blue reversed methemoglobinemia.

    In plain wordsIntravenous methylene blue reversed methemoglobinemia in a man after benzocaine exposure.

    Peptide
    Methylene blue
    Outcome
    DecreaseMethemoglobinemia reversal
    Study

    n = 1

    Outcome group
    Blood oxygenation and oxygen transport · Whole body
    Studied dose
    Dose not stated · intravenousAs given in this study (human).

    Source sentences

    Summary
    Intravenous methylene blue reversed the methemoglobinemia, although delayed recurrence 20 h later necessitated readministration of intravenous methylene blue.
    1 context sentence
    Summary · context
    An 83-year-old man received benzocaine topical anesthesia 600 mg prior to intubation for resection of a thyroid adenoma.
  2. 02HumanCase report or seriesEfficacy outcome

    In a man treated with intravenous methylene blue, methemoglobinemia recurred 20 h later and required readministration.

    In plain wordsMethemoglobinemia returned after intravenous methylene blue in a man and required another dose.

    Peptide
    Methylene blue
    Outcome
    IncreaseMethemoglobinemia recurrence
    Study

    n = 1

    Outcome group
    Blood oxygenation and oxygen transport · Whole body
    Studied dose
    Dose not stated · intravenousAs given in this study (human).

    Measurements

    Time to recurrence of methemoglobinemia
    20 h
    After intravenous methylene blue

    Source sentences

    Summary
    Intravenous methylene blue reversed the methemoglobinemia, although delayed recurrence 20 h later necessitated readministration of intravenous methylene blue.
    1 context sentence
    Summary · context
    An 83-year-old man received benzocaine topical anesthesia 600 mg prior to intubation for resection of a thyroid adenoma.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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