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Study · Measured the body's own peptide · 1995

2 results

Developmental characterization of thymosin beta 4 and beta 10 expression in enriched neuronal cultures from rat cerebella.

Voisin PJ, Pardue S, Morrison-Bogorad M

Journal of neurochemistry1 Jan 1995Cited by 19 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelIn vitro (cells)Mechanism

    In primary rat cerebellar cultures, thymosin beta‑4 was initially expressed in granule cells, but expression was truncated compared with the in vivo time course.

    In plain wordsIn cells from rat cerebellum, the body's own thymosin beta‑4 started in granule cells but ended sooner than in living rats.

    Outcome
    Not applicableThymosin beta 4 expression in granule cells in culture
    Study

    ratn: not reported in source

    Primary cultures of rat cerebellum
    Outcome group
    Gene expression · Nervous system and cognition

    Source sentences

    Summary
    Both beta-thymosins were initially expressed in granule cells, although expression, especially of thymosin beta 4, was truncated compared with the in vivo time course.
    1 context sentence
    Summary · context
    To study the factors differentially regulating expression of the beta-thymosins, we characterized their patterns of expression in primary cultures of rat cerebellum.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelIn vitro (cells)Mechanism

    In primary cultures from postnatal rat cerebellum, thymosin beta‑4 was synthesized at much higher levels in astrocytes and microglia than thymosin beta 10.

    In plain wordsIn cells from rat cerebellum, astrocytes and microglia made much more of the body's own thymosin beta‑4 than thymosin beta-10.

    Outcome
    Not applicableThymosin beta 4 versus beta 10 in astrocytes and microglia
    Study

    ratn: not reported in source

    Primary cultures of rat cerebellum
    Comparator
    Thymosin beta 10
    Outcome group
    Gene expression · Nervous system and cognition

    Source sentences

    Summary
    As in vivo, thymosin beta 4 was synthesized at much higher levels in astrocytes and microglia in cultures from postnatal cerebellum than was thymosin beta 10.
    1 context sentence
    Summary · context
    To study the factors differentially regulating expression of the beta-thymosins, we characterized their patterns of expression in primary cultures of rat cerebellum.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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