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Study · Measured the body's own peptide · 1995

3 results

The thymosin beta 4 gene is strongly activated in neural tissues during early postimplantation mouse development.

Carpinterio P, Anadón R, del Amo FF, Gómez-Márquez J

Neuroscience letters1 Jan 1995Cited by 17 (Europe PMC)

PMID7739809 (opens in a new tab)DOI10.1016/0304-3940(94)11169-j (opens in a new tab)PepBankPUB-07739809
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In postimplantation mouse embryos, total embryo RNA showed strong activation of the thymosin beta‑4 gene after gastrulation, coincident with neurulation.

    In plain wordsIn mouse embryos, the body's own thymosin beta‑4 gene switched on strongly after gastrulation, when the nervous system formed.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseT beta 4 gene activation in total embryo RNA
    Study

    mousen: not reported in source

    Postimplantation mouse embryo
    Outcome group
    Gene expression · Nervous system and cognition

    Source sentences

    Summary
    Analysis of total embryo RNA demonstrated a strong activation of T beta 4 gene after gastrulation and coincident with neurulation.
    1 context sentence
    Summary · context
    We studied the temporal and spatial distribution of the mRNA encoding for thymosin beta 4 (T beta 4), a small acidic actin-sequestering peptide, during the early postimplantation mouse development.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In postimplantation mouse embryos, in situ hybridization showed strong thymosin beta‑4 mRNA expression in the central nervous system and peripheral ganglia, paralleling the gradient of neuronal differentiation.

    In plain wordsIn mouse embryos, the body's own thymosin beta‑4 mRNA was strong in the brain, spinal cord and nerve ganglia.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableT beta 4 mRNA location in nervous system
    Study

    mousen: not reported in source

    Postimplantation mouse embryo
    Outcome group
    Gene expression · Nervous system and cognition

    Source sentences

    Summary
    In situ hybridization showed that T beta 4 mRNA was strongly expressed in the central nervous system and peripheral ganglia, paralleling the gradient of neuronal differentiation.
    1 context sentence
    Summary · context
    We studied the temporal and spatial distribution of the mRNA encoding for thymosin beta 4 (T beta 4), a small acidic actin-sequestering peptide, during the early postimplantation mouse development.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  3. 03AnimalEndogenous levelAnimal study (in vivo)Mechanism

    In postimplantation mouse embryos, an intense thymosin beta‑4 signal was also seen in intraventricular macrophages and blood vessels.

    In plain wordsIn mouse embryos, the body's own thymosin beta‑4 signal was also strong in macrophages inside the brain ventricles and in blood vessels.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableT beta 4 mRNA signal in macrophages and blood vessels
    Study

    mousen: not reported in source

    Postimplantation mouse embryo
    Outcome group
    Gene expression · Nervous system and cognition

    Source sentences

    Summary
    An intense signal was also observed in intraventricular macrophages and blood vessels.
    1 context sentence
    Summary · context
    We studied the temporal and spatial distribution of the mRNA encoding for thymosin beta 4 (T beta 4), a small acidic actin-sequestering peptide, during the early postimplantation mouse development.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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