In rats, gonadorelin in a zinc suspension was less bioavailable than buserelin in a zinc suspension.
In plain wordsIn rats, gonadorelin in a zinc suspension reached the body less well than buserelin in a zinc suspension.
- Peptide
- Gonadorelin (GnRH, LHRH)
- Outcome
- DecreaseBioavailability versus buserelin
- Study
ratn: not reported in source
in vivo, zinc suspension- Comparator
- Buserelin
- Outcome group
- Pharmacokinetics · Pharmacology
- Studied dose
- Dose not stated · subcutaneousAs given in this study (rat).
Source sentences
It has been stated that buserelin in suspension is better available to an organism than gonadorelin .
2 context sentences(design, population, supporting numbers)
There have been determined parameters defining biological availability of gonadorelin and buserelin marked 125 J.
Hormonal preparations were hypodermically administered to the rats in suspensions containing zinc ions of the molar ratio of the hormone: zinc 1:5.