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Study · Case report or series · n = 1 · 1980

1 result

Acute methemoglobinemia induced by topical benzocaine and lidocaine.

O'Donohue WJ Jr, Moss LM, Angelillo VA

Archives of internal medicine1 Nov 1980Cited by 49 (Europe PMC)

Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. 1 result from people.

  1. 01HumanCase report or seriesEfficacy outcome

    In a patient with respiratory failure after trauma, intravenous methylene blue was effective in correcting two episodes of acute methemoglobinemia, one after topical benzocaine and one after lidocaine.

    In plain wordsIn a patient with respiratory failure after trauma, intravenous methylene blue corrected both episodes of methemoglobinemia.

    Outcome
    DecreaseCorrection of methemoglobinemia (two episodes)
    Study

    n = 1

    Outcome group
    Blood oxygenation and oxygen transport · Whole body
    Studied dose
    Dose not stated · intravenousAs given in this study (human).

    Source sentences

    Summary
    On both occasions, intravenous methylene blue was effective in correcting the disorder.
    2 context sentences
    Summary · context
    We describe a patient with respiratory failure following trauma who had two episodes of acute methemoglobinemia, one after the topical application of benzocaine and the second following lidocaine administration for endotracheal intubation.
    Summary · context
    The episodes occurred more than 20 hours apart, and no other drugs known to induce methemoglobinemia were given.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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