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Study · Not a test of the peptide alone · 1980

4 results

[Comparative action of the low-molecular fractions from thymus and cerebral cortex polypeptides on the immune response in mice].

Belokrylov GA, Sofronov BN

Biulleten' eksperimental'noi biologii i meditsiny1 Aug 1980

PMID7407393 (opens in a new tab)PepBankPUB-07407393
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, Cortexin (cortical polypeptide complex) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Cortexin (cortical polypeptide complex).

  1. 01LabNot a test of Cortexin (cortical polypeptide complex) aloneIn vitro (cells)Mechanism

    In laboratory assays, pooled thymus and brain cortex polypeptide effects related to thymus-dependent lymphocytes rather than B cells.

    In plain wordsIn lab tests, pooled thymus and brain cortex polypeptide effects related to thymus-dependent lymphocytes rather than B cells.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    Not applicableLymphocyte population dependence
    Study

    n: not reported in source

    Thymocyte and bone marrow cell cytotoxicity assays
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    The biological effect of the polypeptides from the thymus and brain cortex is related to the thymus-dependent lymphocyte population rather than to B cells.
    2 context sentences
    Summary · context
    Rabbit antisera against low-molecular weight polypeptides from the thymus (thymosin and thymarin), brain cortex (cortexin) and white matter of the calf brain were cross absorbed with these polypeptides and tested in the complement fixation test with the above preparations.
    Summary · context
    In addition they were also tested in the complement-dependent cytotoxicity test with thymocytes and bone marrow cells.

    In this study, Cortexin (cortical polypeptide complex) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cortexin (cortical polypeptide complex).

  2. 02LabNot a test of Cortexin (cortical polypeptide complex) aloneIn vitro (cell-free)Activity measurement

    In antibody assays, cortexin was antigenically similar to thymosin and thymarin but differed from the white-matter polypeptide.

    In plain wordsIn lab tests, cortexin shared antigenic features with thymosin and thymarin but differed from the white-matter polypeptide.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    Not applicableAntigenic similarity
    Study

    n: not reported in source

    Antiserum cross-absorption and complement fixation assays
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Thymosin, thymarin and cortexin were shown to be antigenously similar but to differ in antigenous structure from the polypeptide of brain white matter.
    2 context sentences
    Summary · context
    Rabbit antisera against low-molecular weight polypeptides from the thymus (thymosin and thymarin), brain cortex (cortexin) and white matter of the calf brain were cross absorbed with these polypeptides and tested in the complement fixation test with the above preparations.
    Summary · context
    In addition they were also tested in the complement-dependent cytotoxicity test with thymocytes and bone marrow cells.

    In this study, Cortexin (cortical polypeptide complex) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cortexin (cortical polypeptide complex).

  3. 03LabNot a test of Cortexin (cortical polypeptide complex) aloneIn vitro (cell-free)Activity measurement

    In cross-absorption assays, antisera against brain cortex polypeptides contained antibodies to shared and preparation-specific antigens.

    In plain wordsIn lab tests, antibodies against brain cortex polypeptides recognized shared antigens and antigens specific to the preparation.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    Not applicableCommon and preparation-specific antigens
    Study

    n: not reported in source

    Antiserum cross-absorption and complement fixation assays
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Cross absorption has revealed that antisera against the polypeptides from the thymus and brain cortex contain antyibody both against common antigens and antigens specific only for the appropriate preparation.
    2 context sentences
    Summary · context
    Rabbit antisera against low-molecular weight polypeptides from the thymus (thymosin and thymarin), brain cortex (cortexin) and white matter of the calf brain were cross absorbed with these polypeptides and tested in the complement fixation test with the above preparations.
    Summary · context
    In addition they were also tested in the complement-dependent cytotoxicity test with thymocytes and bone marrow cells.

    In this study, Cortexin (cortical polypeptide complex) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cortexin (cortical polypeptide complex).

  4. 04LabNot a test of Cortexin (cortical polypeptide complex) aloneIn vitro (cell-free)Activity measurement

    In laboratory assays, cortexin antigenic composition corresponded less closely to thymic antigens than thymarin did.

    In plain wordsIn lab tests, cortexin matched thymic antigens less closely than thymarin did.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    DecreaseCorrespondence to thymic antigens
    Study

    n: not reported in source

    Antiserum cross-absorption and complement fixation assays
    Comparator
    Thymarin
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    The antigenous set of thymarin responds better to thymic antigens than cortexin.
    2 context sentences
    Summary · context
    Rabbit antisera against low-molecular weight polypeptides from the thymus (thymosin and thymarin), brain cortex (cortexin) and white matter of the calf brain were cross absorbed with these polypeptides and tested in the complement fixation test with the above preparations.
    Summary · context
    In addition they were also tested in the complement-dependent cytotoxicity test with thymocytes and bone marrow cells.

    In this study, Cortexin (cortical polypeptide complex) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cortexin (cortical polypeptide complex).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:25 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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