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Study · Not a test of the peptide alone · 1980

1 result

C-Peptide reserve in insulin-dependent diabetes. Comparative responses to glucose, glucagon and tolbutamide.

Mirel RD, Ginsberg-Fellner F, Horwitz DL, Rayfield EJ

Diabetologia1 Sept 1980Cited by 35 (Europe PMC)

Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone1

In this study, Glucagon was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Glucagon.

  1. 01HumanNot a test of Glucagon aloneNon-randomized trialActivity measurement

    In short-term diabetic responders, glucagon produced greater C-peptide responses than glucose and tolbutamide, with a mean increase of 0.62 pmol/ml.

    In plain wordsIn short-term diabetic responders, glucagon produced greater C-peptide responses than glucose and tolbutamide, with a mean increase of 0.62 pmol/ml.

    Peptide
    Glucagon
    Outcome
    IncreaseC-peptide response in short-term diabetic responders
    Study

    n: not reported in source

    Comparator
    Glucose and tolbutamide provocative tests
    Outcome group
    Diagnostic Response · Endocrine and hormones

    Measurements

    C-peptide increase
    0.62 pmol/ml
    short-term responders

    Source sentences

    Summary
    The greatest C-peptide responses occurred after glucagon administration (mean increase 0.62 pmol/ml) in short-term responders.
    1 context sentence
    Summary · context
    Residual beta cell secretory capacity was assessed in short term (2 months to 2 years) and long term (5 to 8 years) insulin-dependent diabetics by measurement of serum C-peptide immunoreactivity during three provocative tests: glucose, tolbutamide, and glucagon.

    In this study, Glucagon was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Glucagon.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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