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Study · Measured the body's own peptide · 1984

3 results

Isolation and structural studies of porcine, ovine and murine thymosin beta 4 by high-performance liquid chromatography.

Low TL, Mercer RC

Journal of chromatography1 Sept 1984Cited by 7 (Europe PMC)

PMID6501489 (opens in a new tab)DOI10.1016/s0021-9673(01)89190-1 (opens in a new tab)PepBankPUB-06501489
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured2

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01AnimalEndogenous levelAnimal study (in vivo)Other

    Porcine and ovine thymus fraction 5A and murine spleen 5A each gave a predominant HPLC peak at a retention time similar to bovine thymosin beta‑4.

    In plain wordsIn pigs, sheep and mice, tissue extracts held the body's own peptide that behaved like thymosin beta‑4 in a lab test.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableThymosin beta 4-like peak in porcine, ovine and murine tissue
    Study

    pig, sheep, mousen: not reported in source

    thymus and spleen tissue extracts
    Outcome group
    Endogenous peptide levels · Whole body

    Source sentences

    Summary
    Porcine and ovine thymus fraction 5A, and murine spleen 5A, each yields a predominant peak at a retention time similar to that of bovine thymosin beta 4.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02AnimalEndogenous levelAnimal study (in vivo)Other

    Chromatography of fresh murine thymus and spleen revealed protein peaks at the position of bovine thymosin beta‑4, which suggests native thymosin beta‑4 in these tissues.

    In plain wordsIn mice, thymus and spleen tissue showed a peak that suggests the body's own thymosin beta‑4 is present.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableThymosin beta 4 in fresh murine thymus and spleen
    Study

    mousen: not reported in source

    thymus and spleen tissue extracts
    Outcome group
    Endogenous peptide levels · Whole body

    Source sentences

    Summary
    Chromatographic analysis of fresh murine thymus and spleen tissues also revealed protein peaks at the position of bovine beta 4, suggesting that thymosin beta 4 is the native protein present in the animal tissues.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

Studies that did not test the peptide alone1

In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin beta-4 (human).

  1. 03AnimalNot a test of Thymosin beta-4 (human) aloneAnimal study (in vivo)Other

    Amino acid analysis and HPLC tryptic peptide mapping showed that the peaks have sequences homologous to bovine thymosin beta‑4.

    In plain wordsIn lab tests, the peptide from pig, sheep and mouse tissue had a sequence like bovine thymosin beta‑4.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableSequence homology to bovine thymosin beta 4
    Study

    pig, sheep, mousen: not reported in source

    thymus and spleen tissue extracts
    Outcome group
    Peptide structure and chemistry · Whole body

    Source sentences

    Summary
    Amino acid analysis as well as HPLC tryptic peptide mapping of these peaks indicate that they have homologous sequences to bovine thymosin beta 4.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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