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Study · Randomized controlled trial · n = 188 · 1984

4 results

Hydrostatic reduction of childhood intussusception. The role of adjuvant glucagon medication.

Mortensson W, Eklöf O, Laurin S

Acta radiologica: diagnosis1 Jan 1984Cited by 11 (Europe PMC)

PMID6485854 (opens in a new tab)DOI10.1177/028418518402500402 (opens in a new tab)PepBankPUB-06485854
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. 4 results from people.

  1. 01HumanRandomized controlled trialEfficacy outcome

    In children with intussusception, reduction succeeded in 84 per cent with glucagon versus 76 per cent in controls, without significance.

    In plain wordsIn children with intussusception, glucagon did not significantly improve reduction success versus control.

    Peptide
    Glucagon
    Outcome
    No significant changeSuccessful hydrostatic reduction
    Study

    n = 188

    Comparator
    Control
    Outcome group
    Intussusception Reduction · Gastrointestinal
    Studied dose
    0.05 mg/kg · intramuscularAs given in this study (human).

    Measurements

    Successful reduction
    84%
    glucagon
    Successful reduction
    76%
    control

    Source sentences

    Summary
    The rate of successfully accomplished reductions was 84 per cent in the test group and 76 per cent in the control group (not significant).
    2 context sentences
    Summary · context
    Sixty-nine patients selected at random received 0.05 mg glucagon/kg body weight intramuscularly before attempts at reduction were started.
    Summary · context
    The value of glucagon to facilitate hydrostatic reduction of childhood ileo-colic intussusception was tested in a series of 188 consecutive cases.
  2. 02HumanRandomized controlled trialEfficacy outcome

    In children with intussusception, reduction time was approximately equal with glucagon and control.

    In plain wordsIn children with intussusception, reduction time was approximately equal with glucagon and control.

    Peptide
    Glucagon
    Outcome
    Direction not reportedTime to reduction
    Study

    n = 188

    Comparator
    Control
    Outcome group
    Intussusception Reduction · Gastrointestinal
    Studied dose
    0.05 mg/kg · intramuscularAs given in this study (human).

    Source sentences

    Summary
    The time for accomplished reduction was approximately equal in the two groups.
    2 context sentences
    Summary · context
    Sixty-nine patients selected at random received 0.05 mg glucagon/kg body weight intramuscularly before attempts at reduction were started.
    Summary · context
    The value of glucagon to facilitate hydrostatic reduction of childhood ileo-colic intussusception was tested in a series of 188 consecutive cases.
  3. 03HumanNon-randomized trialSafety outcome

    In the childhood intussusception series, no complications occurred.

    In plain wordsIn the childhood intussusception series, no complications occurred.

    Peptide
    Glucagon
    Outcome
    Not applicableComplications
    Study

    n = 188

    Outcome group
    Adverse events · Gastrointestinal
    Studied dose
    0.05 mg/kg · intramuscularAs given in this study (human).

    Source sentences

    Summary
    No complications occurred.
    2 context sentences
    Summary · context
    Sixty-nine patients selected at random received 0.05 mg glucagon/kg body weight intramuscularly before attempts at reduction were started.
    Summary · context
    The value of glucagon to facilitate hydrostatic reduction of childhood ileo-colic intussusception was tested in a series of 188 consecutive cases.
  4. 04HumanNon-randomized trialEfficacy outcome

    In children after unsuccessful hydrostatic reductions, the subsequent attempt after glucagon succeeded in slightly more than every second case.

    In plain wordsIn children after unsuccessful reductions, the next attempt after glucagon succeeded in slightly more than every second case.

    Peptide
    Glucagon
    Outcome
    Not applicableRescue reduction success
    Study

    n: not reported in source

    Outcome group
    Intussusception Reduction · Gastrointestinal
    Studied dose
    0.05 mg/kg · intramuscularAs given in this study (human).

    Source sentences

    Summary
    The subsequent attempt at reduction proved successful in slightly more than every second case.
    2 context sentences
    Summary · context
    After 3 unsuccessful attempts at hydrostatic reduction patients in the control group received glucagon.
    Summary · context
    Sixty-nine patients selected at random received 0.05 mg glucagon/kg body weight intramuscularly before attempts at reduction were started.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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