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Study · Non-randomized trial · n = 14 · 1983

5 results

Glucagon enhancement of cholangiography. A preliminary report.

Tabak CA, Tuxen PL, Bruce DL, Juler GL

Archives of surgery (Chicago, Ill. : 1960)1 Jan 1983Cited by 7 (Europe PMC)

PMID6336645 (opens in a new tab)DOI10.1001/archsurg.1983.01390010060014 (opens in a new tab)PepBankPUB-06336645
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study5

5 results from studies that gave the peptide. 5 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In patients undergoing cholecystectomy, glucagon significantly improved biliary tree visualization versus saline.

    In plain wordsIn patients undergoing gallbladder surgery, glucagon improved bile duct visualization compared with saline.

    Peptide
    Glucagon
    Outcome
    IncreaseBiliary tree visualization
    Study

    n = 14

    Comparator
    Normal saline
    Outcome group
    Diagnostic Imaging · Gastrointestinal
    Studied dose
    1 mg · intravenousAs given in this study (human).

    Source sentences

    Summary
    There was a consistently superior visualization of the biliary tree in those given glucagon, and the difference was statistically significant.
    2 context sentences
    Summary · context
    Fourteen patients having cholecystectomies under general anesthesia were divided into two groups in a double-blind study.
    Summary · context
    All had intraoperative cholangiograms, before which half had glucagon hydrochloride given intravenously in a dose of 1 mg
  2. 02HumanNon-randomized trialSafety outcome

    In cholecystectomy patients, blood glucose did not change significantly in either the glucagon or saline group.

    In plain wordsIn gallbladder surgery patients, blood sugar did not change significantly in either the glucagon or saline group.

    Peptide
    Glucagon
    Outcome
    No significant changeBlood glucose change
    Study

    n = 14

    Comparator
    Baseline
    Outcome group
    Glycemic control · Metabolic and weight
    Studied dose
    1 mg · intravenousAs given in this study (human).

    Source sentences

    Summary
    No significant changes in blood glucose level, heart rate, or ECG patterns were noted in either group.
    2 context sentences
    Summary · context
    Fourteen patients having cholecystectomies under general anesthesia were divided into two groups in a double-blind study.
    Summary · context
    All had intraoperative cholangiograms, before which half had glucagon hydrochloride given intravenously in a dose of 1 mg
  3. 03HumanNon-randomized trialSafety outcome

    In cholecystectomy patients, heart rate did not change significantly in either the glucagon or saline group.

    In plain wordsIn gallbladder surgery patients, heart rate did not change significantly in either the glucagon or saline group.

    Peptide
    Glucagon
    Outcome
    No significant changeHeart rate change
    Study

    n = 14

    Comparator
    Baseline
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    1 mg · intravenousAs given in this study (human).

    Source sentences

    Summary
    No significant changes in blood glucose level, heart rate, or ECG patterns were noted in either group.
    2 context sentences
    Summary · context
    Fourteen patients having cholecystectomies under general anesthesia were divided into two groups in a double-blind study.
    Summary · context
    All had intraoperative cholangiograms, before which half had glucagon hydrochloride given intravenously in a dose of 1 mg
  4. 04HumanNon-randomized trialSafety outcome

    In cholecystectomy patients, ECG patterns did not change significantly in either the glucagon or saline group.

    In plain wordsIn gallbladder surgery patients, heart electrical patterns did not change significantly in either the glucagon or saline group.

    Peptide
    Glucagon
    Outcome
    No significant changeECG pattern change
    Study

    n = 14

    Comparator
    Baseline
    Outcome group
    Heart function · Cardiovascular
    Studied dose
    1 mg · intravenousAs given in this study (human).

    Source sentences

    Summary
    No significant changes in blood glucose level, heart rate, or ECG patterns were noted in either group.
    2 context sentences
    Summary · context
    Fourteen patients having cholecystectomies under general anesthesia were divided into two groups in a double-blind study.
    Summary · context
    All had intraoperative cholangiograms, before which half had glucagon hydrochloride given intravenously in a dose of 1 mg
  5. 05HumanNon-randomized trialSafety outcome

    One cholecystectomy patient with preoperative hypertension had a brief blood pressure rise after glucagon.

    In plain wordsOne gallbladder surgery patient with high blood pressure had a brief pressure rise after glucagon.

    Peptide
    Glucagon
    Outcome
    IncreaseTransient blood pressure rise
    Study

    n = 1

    Comparator
    Before glucagon
    Outcome group
    Blood pressure · Cardiovascular
    Studied dose
    1 mg · intravenousAs given in this study (human).

    Source sentences

    Summary
    One patient with preoperative hypertension had a brief rise in BP after the glucagon was given.
    2 context sentences
    Summary · context
    Fourteen patients having cholecystectomies under general anesthesia were divided into two groups in a double-blind study.
    Summary · context
    All had intraoperative cholangiograms, before which half had glucagon hydrochloride given intravenously in a dose of 1 mg

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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