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Study · Not a test of the peptide alone · 1980

4 results

[Antigenic similarity between stimulators of immunogenesis of a polypeptide nature from the thymus and cerebral cortex].

Belokrylov GA

Biulleten' eksperimental'noi biologii i meditsiny1 Sept 1980

PMID6159021 (opens in a new tab)PepBankPUB-06159021
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone4

In this study, Cortexin (cortical polypeptide complex) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Cortexin (cortical polypeptide complex).

  1. 01LabNot a test of Cortexin (cortical polypeptide complex) aloneIn vitro (cells)Mechanism

    In laboratory assays, pooled thymus and brain cortex polypeptide effects were linked to thymus-dependent lymphocytes and did not depend on B cells.

    In plain wordsIn lab tests, pooled thymus and brain cortex polypeptide effects involved thymus-dependent lymphocytes and did not depend on B cells.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    Not applicableLymphocyte population dependence
    Study

    n: not reported in source

    Thymic and bone marrow cell cytotoxicity assays
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Biological effect of polypeptides from the thymus and brain cortex is connected with thymus-depending lymphocytes and does not depend on B-cells.
    1 context sentence
    Summary · context
    Rabbit antisera against low molecular weight polypeptides from the thymus (thymosin and thymarin), cortex (cortexin) and white matter of the brain of the calves were cross-absorbed with these polypeptides and tested in the complement fixation test with these preparations

    In this study, Cortexin (cortical polypeptide complex) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cortexin (cortical polypeptide complex).

  2. 02LabNot a test of Cortexin (cortical polypeptide complex) aloneIn vitro (cell-free)Activity measurement

    In antibody assays, cortexin was antigenically similar to thymosin and thymarin but differed from the white-matter polypeptide.

    In plain wordsIn lab tests, cortexin shared antigenic features with thymosin and thymarin but differed from the white-matter polypeptide.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    Not applicableAntigenic similarity
    Study

    n: not reported in source

    Antiserum cross-absorption and complement fixation assays
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    The results showed that thymosin, thymarin and cortexin are antigenically similar, but differ in antigenic structure from polypeptide from white matter of the brain.
    1 context sentence
    Summary · context
    Rabbit antisera against low molecular weight polypeptides from the thymus (thymosin and thymarin), cortex (cortexin) and white matter of the brain of the calves were cross-absorbed with these polypeptides and tested in the complement fixation test with these preparations

    In this study, Cortexin (cortical polypeptide complex) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cortexin (cortical polypeptide complex).

  3. 03LabNot a test of Cortexin (cortical polypeptide complex) aloneIn vitro (cell-free)Activity measurement

    In cross-absorption assays, antisera against cortex polypeptides contained antibodies to both shared and preparation-specific antigens.

    In plain wordsIn lab tests, antibodies against cortex polypeptides recognized shared antigens and antigens specific to the preparation.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    Not applicableCommon and preparation-specific antigens
    Study

    n: not reported in source

    Antiserum cross-absorption and complement fixation assays
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Cross absorbtion revealed that antisera against polypeptides from thymus and cortex of the brain contain antibody both against common antigens and antigens specific for appropriate preparation only.
    1 context sentence
    Summary · context
    Rabbit antisera against low molecular weight polypeptides from the thymus (thymosin and thymarin), cortex (cortexin) and white matter of the brain of the calves were cross-absorbed with these polypeptides and tested in the complement fixation test with these preparations

    In this study, Cortexin (cortical polypeptide complex) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cortexin (cortical polypeptide complex).

  4. 04LabNot a test of Cortexin (cortical polypeptide complex) aloneIn vitro (cell-free)Activity measurement

    In laboratory assays, cortexin antigenic composition corresponded less closely to thymic antigen than thymarin did.

    In plain wordsIn lab tests, cortexin matched thymic antigen less closely than thymarin did.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    DecreaseCorrespondence to thymic antigens
    Study

    n: not reported in source

    Antiserum cross-absorption and complement fixation assays
    Comparator
    Thymarin
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    Antigenic set of polypeptide from the thymus (thymarin) corresponds more closely to thymic antigen as compared to polypeptide from the brain cortex (cortexin).
    1 context sentence
    Summary · context
    Rabbit antisera against low molecular weight polypeptides from the thymus (thymosin and thymarin), cortex (cortexin) and white matter of the brain of the calves were cross-absorbed with these polypeptides and tested in the complement fixation test with these preparations

    In this study, Cortexin (cortical polypeptide complex) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Cortexin (cortical polypeptide complex).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:25 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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