In acute unilateral optic neuritis, corticotrophin gelatin injections produced no significant overall differences from inert injections through two years.
In plain wordsIn acute optic neuritis, corticotrophin gelatin injections did not significantly differ from inert injections through two years.
- Peptide
- ACTH (corticotropin)
- Outcome
- No significant changeOverall optic neuritis outcomes
- Study
n = 54
- Comparator
- Inert injections
- Outcome group
- Vision and retina · Eye
- Studied dose
- Dose not stated · injection · 30 daysAs given in this study (human).
Source sentences
No significant differences were found between treated and control groups at intervals up to two years from the start of the trial.
3 context sentences(design, population, supporting numbers)
The effect of a 30 day course of corticotrophin gelatin injections on the natural history of acute unilateral optic neuritis in 27 patients is reported.
A further 27 patients received inert injections in a double-blind control.
Measurements were made on visual acuity, visual field, macular threshold, and colour vision, and the development of optic atrophy and other neurological episodes was recorded.