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Study · Animal study (in vivo) · rat · 1986

3 results

[Effect of thymalin on thrombocyte aggregation and the antiaggregation activity of the vascular wall in intact and thymectomized rats].

Kuznik BI, Makhakova GCh, Morozov VG, Pisarevskaia LI, Khavinson VKh

Farmakologiia i toksikologiia1 Mar 1986

PMID3754821 (opens in a new tab)PepBankPUB-03754821
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Mechanism

    In intact rats, thymalin reduced platelet aggregation ability.

    In plain wordsIn intact rats, thymalin reduced platelets' ability to aggregate.

    Peptide
    Thymalin
    Outcome
    DecreasePlatelet aggregation ability
    Study

    ratn: not reported in source

    Intact rats
    Outcome group
    Bleeding and clotting · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of immunomodulator thymalin to intact rats was shown to produce reduction of platelet aggregation ability and to exert no effect on antiaggregation activity of the aorta.
  2. 02AnimalAnimal study (in vivo)Mechanism

    In intact rats, thymalin did not affect aortic antiaggregation activity.

    In plain wordsIn intact rats, thymalin did not change the aorta's activity against platelet aggregation.

    Peptide
    Thymalin
    Outcome
    No significant changeAortic antiaggregation activity
    Study

    ratn: not reported in source

    Intact rats
    Outcome group
    Bleeding and clotting · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Administration of immunomodulator thymalin to intact rats was shown to produce reduction of platelet aggregation ability and to exert no effect on antiaggregation activity of the aorta.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In thymectomized rats, thymalin normalized platelet hemostasis parameters.

    In plain wordsIn rats with the thymus removed, thymalin normalized measures of platelet clotting function.

    Peptide
    Thymalin
    Outcome
    Direction not reportedPlatelet hemostasis parameters
    Study

    ratn: not reported in source

    Thymectomized rats
    Outcome group
    Bleeding and clotting · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Thymalin administration to thymectomized rats normalizes platelet hemostasis parameters.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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