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Study · Animal study (in vivo) · rat · 1988

2 results

[Influence of the polypeptide preparations cortexin and encephalin on the transplacental carcinogenic effect of N-nitroso-N-ethylurea in rats].

Bespalov VG, Aleksandrov VA, Morozov VG, Khavinson VKh

Eksperimental'naia onkologiia1 Jan 1988Cited by 1 (Europe PMC)

PMID3391119 (opens in a new tab)PepBankPUB-03391119
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

2 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats exposed transplacentally to carcinogen, postnatal cortexin decreased brain tumor incidence.

    In plain wordsIn rats exposed to a carcinogen before birth, cortexin decreased brain tumor incidence.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    DecreaseBrain tumor incidence
    Study

    ratn: not reported in source

    Transplacental N-nitroso-N-ethylurea-induced tumors
    Outcome group
    Tumor growth · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The two preparations decreased both the incidence and multiplicity of the brain tumours.
    1 context sentence
    Summary · context
    The polypeptide preparations cortexin and encephalin from grey and white substances of the cattle brain injected in the postnatal period are studied for their effect on the development of the nervous system and kidney tumours in rats induced transplacentally by N-nitroso-N-ethylurea.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rats exposed transplacentally to carcinogen, postnatal cortexin decreased brain tumor multiplicity.

    In plain wordsIn rats exposed to a carcinogen before birth, cortexin decreased the number of brain tumors.

    Peptide
    Cortexin (cortical polypeptide complex)
    Outcome
    DecreaseBrain tumor multiplicity
    Study

    ratn: not reported in source

    Transplacental N-nitroso-N-ethylurea-induced tumors
    Outcome group
    Tumor growth · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    The two preparations decreased both the incidence and multiplicity of the brain tumours.
    1 context sentence
    Summary · context
    The polypeptide preparations cortexin and encephalin from grey and white substances of the cattle brain injected in the postnatal period are studied for their effect on the development of the nervous system and kidney tumours in rats induced transplacentally by N-nitroso-N-ethylurea.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    22 Oct 2026, 02:25 UTC

    Study results updated

  2. Version 1

    21 Oct 2026, 18:59 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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