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Study · Animal study (in vivo) · rat · 1988

1 result

[Effect of tocopherol, phenformin and thymus and pineal polypeptide factors on the transplacental carcinogenic effect of N-nitroso-N-ethylurea in rats].

Bespalov VG, Aleksandrov VA, Morozov VG, Khavinson VKh

Voprosy onkologii1 Jan 1988Cited by 1 (Europe PMC)

PMID3341127 (opens in a new tab)PepBankPUB-03341127
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats exposed transplacentally to ENU, postnatal thymalin treatment did not significantly influence carcinogenicity.

    In plain wordsIn rats exposed to ENU before birth, thymalin treatment after birth did not significantly change carcinogenicity.

    Peptide
    Thymalin
    Outcome
    No significant changeTransplacental carcinogenicity
    Study

    ratn: not reported in source

    Transplacental N-ethyl-N-nitrosourea exposure
    Outcome group
    Tumor growth · Cancer
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Treatment with tocopherol, thymalin or epithalamin did not significantly influence the transplacental carcinogenicity of ENU, whereas application of phenformin was followed by a decreased incidence of brain tumors.
    1 context sentence
    Summary · context
    The study was concerned with the influence of postnatal treatment with antioxidant tocopherol, antidiabetic drug phenformin and low-molecular polypeptide factors of the thymus (thymalin) and pineal gland (epithalamin) on transplacental carcinogenicity

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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