In bypass patients, post-treatment vWF concentration differences between desmopressin and placebo, although small, correlated better with reduced blood loss than differences in multimer distribution.
In plain wordsIn bypass patients, small differences in vWF concentration between desmopressin and placebo correlated better with reduced blood loss than multimer differences.
- Peptide
- Desmopressin
- Outcome
- Not applicablevWF concentration association with blood loss
- Study
n = 70
- Comparator
- Placebo
- Outcome group
- Bleeding and clotting · Whole body
- Studied dose
- Dose not stated
Source sentences
Differences in the concentration of vWF between desmopressin and placebo patients after receipt of the drug, although small, were better correlated with reduced blood loss than were differences in HMWM distribution.
1 context sentence(design, population, supporting numbers)
To study the mechanism of improved hemostasis in bypass patients, we examined the relationship between von Willebrand factor (vWF) and blood loss in 70 cardiopulmonary bypass patients, one-half of whom received desmopressin intraoperatively. vWF concentration and multimeric composition were analyzed…