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Study · Measured the body's own peptide · 1986

3 results

Thymosin beta 4 is a shared antigen between lymphoid cells and oligodendrocytes of normal human brain.

Dalakas MC, Trapp BD

Annals of neurology1 Apr 1986Cited by 22 (Europe PMC)

PMID3085577 (opens in a new tab)DOI10.1002/ana.410190407 (opens in a new tab)PepBankPUB-03085577
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelEx vivo tissueOther

    In normal human brain tissue, antiserum against thymosin alpha‑1 did not react where thymosin beta 4 was detected.

    In plain wordsIn human brain tissue, an antibody to the body's own thymosin alpha‑1 did not stain the cells that carried thymosin beta 4.

    Peptide
    Thymosin alpha-1
    Outcome
    No significant changeThymosin alpha 1 immunoreactivity in human brain
    Study

    humann: not reported in source

    normal human brain tissue
    Outcome group
    Immune response · Nervous system and cognition

    Source sentences

    Summary
    Antisera directed against two other thymic polypeptides, thymosin alpha 1 and alpha 7, did not react.
    1 context sentence
    Summary · context
    In the normal human brain, immunoreactive thymosin beta 4, a well-characterized thymic extract, was demonstrated specifically in the cell bodies and processes of a subset of interfascicular and satellite oligodendrocytes with their stained processes terminating around myelin sheaths.

    This result measures the body's own Thymosin alpha-1. Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelEx vivo tissueOther

    In normal human brain, immunoreactive thymosin beta‑4 was present in a subset of interfascicular and satellite oligodendrocytes.

    In plain wordsIn normal human brain tissue, the body's own thymosin beta‑4 was found in a subset of oligodendrocytes.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableThymosin beta 4 immunoreactivity in brain oligodendrocytes
    Study

    humann: not reported in source

    Normal human brain and lymphoid tissue sections
    Outcome group
    Endogenous peptide levels · Nervous system and cognition

    Source sentences

    Summary
    In the normal human brain, immunoreactive thymosin beta 4, a well-characterized thymic extract, was demonstrated specifically in the cell bodies and processes of a subset of interfascicular and satellite oligodendrocytes with their stained processes terminating around myelin sheaths.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelEx vivo tissueOther

    In lymphoid tissues, thymosin beta‑4 was present in macrophages, Langerhans' cells of the skin and interdigitating cells of the thymus.

    In plain wordsIn human lymphoid tissue, the body's own thymosin beta‑4 was found in macrophages and several other immune cells.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableThymosin beta 4 immunoreactivity in lymphoid tissues
    Study

    humann: not reported in source

    Normal human brain and lymphoid tissue sections
    Outcome group
    Endogenous peptide levels · Immune and inflammation

    Source sentences

    Summary
    In lymphoid tissues, thymosin beta 4 was present in macrophages, Langerhans' cells of the skin, and the interdigitating cells of the thymus.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 4Current

    12 Oct 2026, 18:17 UTC

    Study data updated · source update from Europe PMC

  2. Version 3

    10 Oct 2026, 08:55 UTC

    Study results updated

  3. Version 2

    9 Oct 2026, 03:03 UTC

    Study data updated · source update from Europe PMC

  4. Version 1

    9 Oct 2026, 03:02 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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