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Study · Animal study (in vivo) · rat · 1987

1 result

Failure of ACTH to alter transfer kindling in the immature brain.

Thompson J, Holmes GL

Epilepsia1 Jan 1987Cited by 10 (Europe PMC)

PMID3024958 (opens in a new tab)DOI10.1111/j.1528-1157.1987.tb03615.x (opens in a new tab)PepBankPUB-03024958
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study1

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In immature rats, ACTH gel did not significantly alter the rate of contralateral amygdala transfer kindling compared with controls.

    In plain wordsIn rats, ACTH gel did not significantly change transfer kindling compared with controls.

    Peptide
    ACTH (corticotropin)
    Outcome
    No significant changeRate of transfer kindling
    Study

    ratn: not reported in source

    Previously amygdala-kindled immature rats
    Comparator
    Controls
    Outcome group
    Neuroprotection · Nervous system and cognition
    Studied dose
    Dose not stated · 15 daysAs given in this study (rat).

    Source sentences

    Summary
    There were no significant differences in the rate of transfer kindling between the controls and ACTH-treated rats.
    1 context sentence
    Summary · context
    For a study of the effects of ACTH on established seizures, 16-day-old rats that had been previously kindled in the amygdala were given a high daily dosage of ACTH gel for 15 days and then underwent transfer kindling in the contralateral amygdala.

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    28 Oct 2026, 02:03 UTC

    Study results updated

  2. Version 1

    27 Oct 2026, 16:35 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

Publication types

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