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Study · Measured the body's own peptide · 1985

3 results

Biosynthesis rates and content of thymosin beta 4 in cell lines.

Hannappel E, Leibold W

Archives of biochemistry and biophysics1 Jul 1985Cited by 63 (Europe PMC)

PMID2990345 (opens in a new tab)DOI10.1016/0003-9861(85)90028-1 (opens in a new tab)PepBankPUB-02990345
Publisher pagePubMedAsk about this study
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

No result from this study comes from a test of the peptide.

Natural levels measured3

These results measure the body's own peptide. Nobody was given the peptide. They are not evidence about taking it. They are left out of key results, evidence counts and charts.

  1. 01LabEndogenous levelIn vitro (cells)Other

    Across 28 cell lines, Epstein-Barr virus-transformed human B-cell lines had the highest content and biosynthesis rate of the cells' own thymosin beta‑4.

    In plain wordsIn cells, Epstein-Barr virus-transformed B-cell lines made and held more of their own thymosin beta‑4 than the other cell lines tested.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableThymosin beta 4 content and biosynthesis across cell lines
    Study

    humann = 28

    28 cell lines
    Outcome group
    Endogenous peptide levels · Whole body

    Source sentences

    Summary
    The highest content of thymosin beta 4 as well as the highest rate of biosynthesis was observed in Epstein-Barr virus-transformed human B-cell lines.
    1 context sentence
    Summary · context
    The content and relative biosynthetic rates of thymosin beta 4 have been determined in 28 different cell lines.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  2. 02LabEndogenous levelIn vitro (cells)Other

    Epstein-Barr virus-transformed B-cell lines held 1 pg of thymosin beta‑4 per cell, three times the level in rat peritoneal macrophages.

    In plain wordsIn cells, B-cell lines held 1 pg of their own thymosin beta‑4 per cell, three times the level in rat macrophages.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableThymosin beta 4 content per cell in B-cell lines
    Study

    humann: not reported in source

    28 cell lines
    Comparator
    Rat peritoneal macrophages
    Outcome group
    Endogenous peptide levels · Whole body

    Measurements

    Thymosin beta 4 content
    1 pg per cell
    EBV-transformed B-cell lines

    Source sentences

    Summary
    The levels observed in these cells are 1 pg thymosin beta 4 per cell, which is three times higher than that in rat peritoneal macrophages.
    1 context sentence
    Summary · context
    The content and relative biosynthetic rates of thymosin beta 4 have been determined in 28 different cell lines.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

  3. 03LabEndogenous levelIn vitro (cells)Other

    Viable Epstein-Barr virus-transformed B cells in culture did not secrete thymosin beta‑4.

    In plain wordsIn cells, viable B cells did not release their own thymosin beta‑4 into the culture.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableSecretion of thymosin beta 4
    Study

    humann: not reported in source

    28 cell lines
    Outcome group
    Endogenous peptide levels · Whole body

    Source sentences

    Summary
    Thymosin beta 4 is not secreted by viable Epstein-Barr virus-transformed B cells in culture, suggesting some intracellular function of the peptide.
    1 context sentence
    Summary · context
    The content and relative biosynthetic rates of thymosin beta 4 have been determined in 28 different cell lines.

    This result measures the body's own Thymosin beta-4 (human). Nobody was given the peptide. It is not evidence about taking it.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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