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Study · Animal study (in vivo) · rabbit · 1988

4 results

[Effect of thymalin on the development of experimental hyperlipidemia and atherosclerosis].

Ryzhenkov VE, Ogurtsov RP, Trubacheva VV, Popov VG, Puzyreva VP

Voprosy meditsinskoi khimii1 Jan 1988

PMID2967015 (opens in a new tab)PepBankPUB-02967015
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

4 results from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rabbits maintained on a cholesterol-containing diet, thymalin exhibited hypolipidemic activity.

    In plain wordsIn rabbits fed a cholesterol-containing diet, thymalin reduced high lipid levels.

    Peptide
    Thymalin
    Outcome
    DecreaseHyperlipidemia
    Study

    rabbitn: not reported in source

    Cholesterol-diet hyperlipidemia
    Outcome group
    Lipids · Metabolic and weight
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Thymalin, which is a polypeptide preparation from thymus, exhibited hypolipidemic and antiatherosclerotic actions in rabbits maintained on a cholesterol-containing diet during three months.
  2. 02AnimalAnimal study (in vivo)Efficacy outcome

    In rabbits maintained on a cholesterol-containing diet, thymalin exhibited antiatherosclerotic activity.

    In plain wordsIn rabbits fed a cholesterol-containing diet, thymalin reduced atherosclerosis.

    Peptide
    Thymalin
    Outcome
    DecreaseAtherosclerosis
    Study

    rabbitn: not reported in source

    Cholesterol-diet hyperlipidemia
    Outcome group
    Cardiovascular events · Cardiovascular
    Studied dose
    Dose not stated

    Source sentences

    Summary
    Thymalin, which is a polypeptide preparation from thymus, exhibited hypolipidemic and antiatherosclerotic actions in rabbits maintained on a cholesterol-containing diet during three months.
  3. 03AnimalAnimal study (in vivo)Mechanism

    In hyperlipidemic rabbits, thymalin normalized T-suppressor activity.

    In plain wordsIn rabbits with high lipid levels, thymalin normalized T-suppressor activity.

    Peptide
    Thymalin
    Outcome
    Not applicableT-suppressor activity
    Study

    rabbitn: not reported in source

    Cholesterol-diet hyperlipidemia
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    At the same time, thymalin caused favourable effect on the functional activity of lymphocytes impaired in hyperlipidemic animals, i.e. it normalized the T-suppressor activity and sensitivity to atherogenic lipoproteins.
  4. 04AnimalAnimal study (in vivo)Mechanism

    In hyperlipidemic rabbits, thymalin normalized lymphocyte sensitivity to atherogenic lipoproteins.

    In plain wordsIn rabbits with high lipid levels, thymalin normalized lymphocyte sensitivity to atherogenic lipoproteins.

    Peptide
    Thymalin
    Outcome
    Not applicableLymphocyte sensitivity to atherogenic lipoproteins
    Study

    rabbitn: not reported in source

    Cholesterol-diet hyperlipidemia
    Outcome group
    Immune response · Immune and inflammation
    Studied dose
    Dose not stated

    Source sentences

    Summary
    At the same time, thymalin caused favourable effect on the functional activity of lymphocytes impaired in hyperlipidemic animals, i.e. it normalized the T-suppressor activity and sensitivity to atherogenic lipoproteins.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

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