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Study · Non-randomized trial · n = 20 · 1988

3 results

[Hypothalamic amenorrhea. Diagnostic and therapeutic values of pulsatile administration of gonadorelin].

Fenichel P, Guedj AM, Verdino P, Brucker F, Strulo S, Mehouas C, Harter M

Presse medicale (Paris, France : 1983)1 Jan 1988Cited by 1 (Europe PMC)

PMID2964021 (opens in a new tab)PepBankPUB-02964021
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Summary

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Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study3

3 results from studies that gave the peptide. 3 results from people.

  1. 01HumanNon-randomized trialEfficacy outcome

    In 20 women with hypothalamic amenorrhea who wished to become pregnant, pulsatile gonadorelin led to 17 pregnancies (85%).

    In plain wordsIn 20 women who wished to become pregnant, pulsed gonadorelin led to 17 pregnancies.

    Peptide
    Gonadorelin (GnRH, LHRH)
    Outcome
    IncreasePregnancies after ovulation induction
    Study

    n = 20

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Measurements

    Pregnancies
    17 pregnancies
    20 women
    Pregnancy rate
    85%
    20 women

    Source sentences

    Summary
    In women wishing to become pregnant, this treatment proved valuable to induce ovulation, being remarkably effective (17 pregnancies in 20 women (85 p.
  2. 02HumanNon-randomized trialEfficacy outcome

    In women who wished to become pregnant, pulsatile gonadorelin needed 2.2 cycles per pregnancy.

    In plain wordsIn women who wished to become pregnant, pulsed gonadorelin needed 2.2 cycles per pregnancy.

    Peptide
    Gonadorelin (GnRH, LHRH)
    Outcome
    Not applicableCycles per pregnancy
    Study

    n = 20

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Measurements

    Cycles per pregnancy
    2.2 cycles/pregnancy
    pulsatile gonadorelin

    Source sentences

    Summary
    2.2 cycles/pregnancy
    1 context sentence
    Summary · context
    In women wishing to become pregnant, this treatment proved valuable to induce ovulation, being remarkably effective (17 pregnancies in 20 women (85 p.
  3. 03HumanNon-randomized trialOther

    In 18 patients with hypogonadotropic hypogonadism, pulsatile gonadorelin given by portable pump allowed a precise topographical diagnosis after the simple gonadotropin-releasing hormone test failed.

    In plain wordsIn 18 patients with hypogonadotropic hypogonadism, pulsed gonadorelin from a portable pump helped locate the cause after a simple test failed.

    Peptide
    Gonadorelin (GnRH, LHRH)
    Outcome
    Not applicableTopographical diagnosis of hypothalamic amenorrhea
    Study

    n = 18

    Outcome group
    Sex hormones and fertility · Reproductive and sexual health
    Studied dose
    Dose not stated

    Source sentences

    Summary
    In 18 patients with hypogonadotropic hypogonadism a precise topographical diagnosis could be made by pulsatile administration of this hormone using a portable pump, after failure of the simple gonadotropin-releasing hormone test (100 micrograms intravenously).

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Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 21:44 UTC

    Study results updated

  2. Version 1

    13 Oct 2026, 16:31 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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