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Study · Animal study (in vivo) · rat · 1987

4 results

[Type-II alveolocytes in the treatment of the pulmonary form of oxygen poisoning (electron microscopic and morphometric research)].

Zaĭtseva KK, Grigor'eva IuA, Lotovin AP

Arkhiv anatomii, gistologii i embriologii1 Dec 1987

PMID2833877 (opens in a new tab)PepBankPUB-02833877
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study4

1 result from studies that gave the peptide. No result from this study comes from people.

  1. 01AnimalAnimal study (in vivo)Efficacy outcome

    In rats with oxygen poisoning, thymalin increased alveolocyte lamellar body relative volume by 1.5 times versus untreated animals.

    In plain wordsIn rats with oxygen poisoning, thymalin increased alveolocyte lamellar body relative volume by 1.5 times compared with untreated animals.

    Peptide
    Thymalin
    Outcome
    IncreaseAlveolocyte lamellar body relative volume
    Study

    ratn: not reported in source

    Pulmonary oxygen poisoning
    Comparator
    Untreated animals
    Outcome group
    Lung injury and fibrosis · Respiratory
    Studied dose
    Dose not stated · 3 daysAs given in this study (rat).

    Measurements

    Relative lamellar body volume
    1.5 times
    Compared with untreated animals

    Source sentences

    Summary
    While treating the pulmonary form of oxygen poisoning with cytochrome C or thymalin, in 3 days after beginning to administer the preparations, the relative volume of the lamellar bodies increase by 1.5 times in comparison with those in the group of untreated animals
    1 context sentence
    Summary · context
    The effect of cytochrome C, thymalin and their combination has been studied concerning morphofunctional state of alveolocytes of the II type (A II) in the lungs of 33 non-inbred white rats at the pulmonary form of oxygen poisoning.

Studies that did not test the peptide alone3

In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymalin.

  1. 02AnimalNot a test of Thymalin aloneAnimal study (in vivo)Efficacy outcome

    In rats with oxygen poisoning, combined cytochrome C and thymalin increased alveolocyte lamellar body relative volume by 2.5 times versus untreated animals.

    In plain wordsIn oxygen-poisoned rats, cytochrome C plus thymalin increased alveolocyte lamellar body relative volume by 2.5 times compared with untreated animals.

    Peptide
    Thymalin
    Outcome
    IncreaseAlveolocyte lamellar body relative volume with combination
    Study

    ratn: not reported in source

    Pulmonary oxygen poisoning
    Comparator
    Untreated animals
    Outcome group
    Lung injury and fibrosis · Respiratory

    Measurements

    Relative lamellar body volume
    2.5 times
    Combination compared with untreated animals

    Source sentences

    Summary
    and at the combined administration-by 2.5 times.
    2 context sentences
    Summary · context
    While treating the pulmonary form of oxygen poisoning with cytochrome C or thymalin, in 3 days after beginning to administer the preparations, the relative volume of the lamellar bodies increase by 1.5 times in comparison with those in the group of untreated animals
    Summary · context
    The effect of cytochrome C, thymalin and their combination has been studied concerning morphofunctional state of alveolocytes of the II type (A II) in the lungs of 33 non-inbred white rats at the pulmonary form of oxygen poisoning.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  2. 03AnimalNot a test of Thymalin aloneAnimal study (in vivo)Efficacy outcome

    In oxygen-poisoned rats, combined cytochrome C and thymalin produced mitochondrial relative volume similar to intact animals by the 3d day.

    In plain wordsIn oxygen-poisoned rats, mitochondrial relative volume after cytochrome C plus thymalin did not differ from intact animals by the 3d day.

    Peptide
    Thymalin
    Outcome
    No significant changeMitochondrial relative volume with combination
    Study

    ratn: not reported in source

    Pulmonary oxygen poisoning
    Comparator
    Intact animals
    Outcome group
    Mitochondrial function · Respiratory

    Source sentences

    Summary
    When the preparations are applied together, by the 3d day the relative volume of mitochondria and amount of A II do not differ from the corresponding indices in intact animals.
    1 context sentence
    Summary · context
    The effect of cytochrome C, thymalin and their combination has been studied concerning morphofunctional state of alveolocytes of the II type (A II) in the lungs of 33 non-inbred white rats at the pulmonary form of oxygen poisoning.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

  3. 04AnimalNot a test of Thymalin aloneAnimal study (in vivo)Efficacy outcome

    In oxygen-poisoned rats, combined cytochrome C and thymalin produced type-II alveolocyte numbers similar to intact animals by the 3d day.

    In plain wordsIn rats with oxygen poisoning, alveolocyte numbers after cytochrome C plus thymalin did not differ from intact animals by the 3d day.

    Peptide
    Thymalin
    Outcome
    No significant changeType-II alveolocyte number with combination
    Study

    ratn: not reported in source

    Pulmonary oxygen poisoning
    Comparator
    Intact animals
    Outcome group
    Cell viability and death · Respiratory

    Source sentences

    Summary
    When the preparations are applied together, by the 3d day the relative volume of mitochondria and amount of A II do not differ from the corresponding indices in intact animals.
    1 context sentence
    Summary · context
    The effect of cytochrome C, thymalin and their combination has been studied concerning morphofunctional state of alveolocytes of the II type (A II) in the lungs of 33 non-inbred white rats at the pulmonary form of oxygen poisoning.

    In this study, Thymalin was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymalin.

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    14 Oct 2026, 05:02 UTC

    Study results updated

  2. Version 1

    14 Oct 2026, 01:46 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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