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Study · Not a test of the peptide alone · 1989

2 results

Synthesis of a thymosin beta 4-like peptide, deacetyl-thymosin beta Xen4, and its restorative effect on depressed lymphocyte blastogenic response to phytohemagglutinin (PHA) in uremic patients.

Abiko T, Sekino H

Chemical & pharmaceutical bulletin1 Sept 1989Cited by 4 (Europe PMC)

PMID2605693 (opens in a new tab)DOI10.1248/cpb.37.2467 (opens in a new tab)PepBankPUB-02605693
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Summary

The text of this summary is not shown here, because the article license does not allow reuse. Read it at the source (opens in a new tab)

Text rights: Publisher copyright. Results still quote short attributed sentences.

Results from this study2

No result from this study comes from a test of the peptide.

Studies that did not test the peptide alone2

In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. These results are not evidence about taking Thymosin beta-4 (human).

  1. 01LabNot a test of Thymosin beta-4 (human) aloneEx vivo tissueActivity measurement

    In T-lymphocytes from uremic patients, the synthetic tritetracontapeptide deacetyl-thymosin beta Xen4 restored the impaired blastogenic response.

    In plain wordsIn lab tests on uremic blood cells, a peptide similar to thymosin beta‑4 restored a weakened immune cell response.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    IncreaseBlastogenic response of T-lymphocytes to PHA
    Study

    humann: not reported in source

    T-lymphocytes isolated from uremic patients
    Outcome group
    Immune response · Immune and inflammation

    Source sentences

    Summary
    The synthetic tritetracontapeptide was found to have a restoring effect on the impaired blastogenic response of T-lymphocytes isolated from uremic patients.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

  2. 02LabNot a test of Thymosin beta-4 (human) aloneIn vitro (cell-free)Other

    An analog of thymosin beta Xen4, deacetyl-thymosin beta Xen4, was synthesized by assembling 6 peptide fragments.

    In plain wordsIn the lab, a peptide similar to thymosin beta‑4, called deacetyl-thymosin beta Xen4, was made by chemical synthesis.

    Peptide
    Thymosin beta-4 (human)
    Outcome
    Not applicableChemical synthesis of deacetyl-thymosin beta Xen4
    Study

    n: not reported in source

    Outcome group
    Synthesis and manufacturing · Pharmacology

    Source sentences

    Summary
    deacetyl-thymosin beta Xen4, was synthesized by assembling 6 peptide fragments, followed by deprotection with 1 M trifluoromethanesulfonic acid-thioanisole (molar ratio, 1:1) in trifluoroacetic acid in the presence of dimethylselenium.

    In this study, Thymosin beta-4 (human) was a lab tool or a carrier, part of a mix, or the subject of a lab method. This result is not evidence about taking Thymosin beta-4 (human).

AI wrote and checked these results. AI can make mistakes, so check important results against the source.

Version history

PepBank keeps every version of the data on this study. Status changes from Retraction Watch, Europe PMC and Crossref are listed with their source.

  1. Version 2Current

    13 Oct 2026, 01:52 UTC

    Study results updated

  2. Version 1

    12 Oct 2026, 18:17 UTC

    First added · source update from Europe PMC

Subjects

Terms as the source lists them.

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